Bioactivity of bioresorbable composite based on bioactive glass and poly-L-lactide

• Published in: Transactions of Nonferrous Metals Society of China Vol. 17; no. 2; pp. 394 - 399
• Main Author: 周智华 阮建明 邹俭鹏 周忠诚 申雄军
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.04.2007; State Key Laboratory of Powder Metallurgy, Central South University, Changsha 410083, China; College of Chemistry and Chemical Engineering, Hunan University of Science and Technology,Xiangtan 411201, China%State Key Laboratory of Powder Metallurgy, Central South University, Changsha 410083, China
• Subjects: bioactive glass; bioactivity; composite; poly-L-lactide; 复合材料; 生物可再吸收性; 生物活性; 聚乳酸; bioactive glass; poly-L-lactide; bioactivity; composite
• ISSN: 1003-6326
• DOI: 10.1016/S1003-6326(07)60105-8

Bioactive and bioresorbable composite was fabricated by a solvent evaporation technique using poly-L-lactide（PLLA） and bioactive glass （average particle size： 6.8μm）. Bioactive glass granules are homogeneously distributed in the composite with microcrack structure. The formation of hydroxyapatite（HA） on the composite in simulated body fluid（SBF） was analyzed by scanning electron microscopy（SEM）, energy dispersive spectroscopy（EDS）, X-ray diffraction（XRD）, and Raman spectra. Rod-like HA crystals deposit on the surface of PLLA/bioactive glass composite after soaking for 3 d. Both rod-like crystals and HA layer form on the surface for 14 d in SBF. The high bioactivity of PLLA/bioactive glass composite indicates the potential of materials for integration with bone.