Evidence of Toscana Virus Circulation in Umbria: First Report

• Published in: European journal of epidemiology Vol. 18; no. 5; pp. 457 - 459
• Main Authors: Francisci, D., Papili, R., Camanni, G., Morosi, S., Ferracchiato, N., Valente, M., Ciufolini, M. G., Baldelli, F.
• Format: Journal Article
• Language: English
• Published: Dordrecht Kluwer Academic Publishers 01.01.2003; Springer; Springer Nature B.V
• Subjects: Adolescent; Adult; Aged; Antibodies; Biological and medical sciences; Cohort Studies; Enzyme-Linked Immunosorbent Assay; Female; Human viral diseases; Humans; Immunoglobulin G - blood; Immunoglobulin G - immunology; Immunoglobulin M - blood; Immunoglobulin M - immunology; Infections; Infectious Diseases; Italy - epidemiology; Male; Medical sciences; Meningitis - blood; Meningitis - epidemiology; Meningitis - virology; Meningoencephalitis; Meningoencephalitis - blood; Meningoencephalitis - epidemiology; Meningoencephalitis - virology; Middle Aged; Phlebotomus fever; Phlebotomy; Phlebovirus; Sandfly fever Naples virus; Sandfly fever Naples virus - immunology; Sandfly fever Naples virus - isolation & purification; Sandfly fever Naples virus - pathogenicity; Seroepidemiologic Studies; Viral diseases; Viral diseases of the nervous system; Viral meningitis; Viruses; Italy; Europe; Umbria; Umbria Italy; Human; Nervous system diseases; Insecta; CNS diseases; Psychodidae; Toscana-virus circulation; Umbria region; Epidemiology; Meningoencephalitis; Infection; Phlebotomus; Arthropoda; Viral disease; Central nervous system disease; Meningitis; Toscana virus; Invertebrata; Diptera; Public health
• ISSN: 0393-2990; 1573-7284
• DOI: 10.1023/A:1024295710118

To evaluate, for the first time, circulation and clinical expression of Toscana virus (ToSv) in Umbria region we studied: (1) 93 cases of aseptic meningitis and meningoencephalitis admitted to our Department from 1989 to 2001 with negative results for common neurotropic virus; (2) 50 healthy subjects. Specific antibodies (IgM and IgG) anti-TOSv were found in 36.6% of aseptic meningitis, in 6.06% of meningoencephalitis and (IgG) in 16% of healthy subjects.