A light addressable electrode with a TiO2 nanocrystalline film for localized electrical stimulation of cultured neurons
To improve the existing light-addressable electrode (LAE) for neuronal stimulation, we attempted to replace a photoconductive layer of hydrogenated amorphous silicon (a-Si:H), which is subject to corrosion in cell culture environments, with a TiO2 nanocrystalline film. As seen in previous LAEs with...
Saved in:
| Published in | Sensors and actuators. B, Chemical Vol. 192; pp. 393 - 398 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Elsevier B.V
01.03.2014
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0925-4005 1873-3077 |
| DOI | 10.1016/j.snb.2013.10.139 |
Cover
| Abstract | To improve the existing light-addressable electrode (LAE) for neuronal stimulation, we attempted to replace a photoconductive layer of hydrogenated amorphous silicon (a-Si:H), which is subject to corrosion in cell culture environments, with a TiO2 nanocrystalline film. As seen in previous LAEs with a-Si:H, the TiO2 film formed on a metal film electrode serves as a photo-switch: UV light illumination locally increases the conductivity of the TiO2 film and generates a virtual electrode. TiO2 is a lower cost material, easier to fabricate than a-Si:H, and more compatible with cell culture environments; thus, it does not require a passivation layer on top. The measurements of photoelectric characteristics of TiO2 LAE ascertained that adequate photo-switching properties for selective neuronal stimulation were achieved; however, two possible issues that could affect performance were identified: degradation of the photo-switching property due to electrolyte penetration into the TiO2 film and a slow switching response due to charge carrier trapping into surface defects. Despite these issues, however, the feasibility of light-addressed electrical stimulation with the proposed TiO2 LAE was successfully demonstrated in an experiment using a primary neuron-glia co-culture. Thus, TiO2 is an alternative candidate to a-Si:H in photo-electrochemical biointerfaces. |
|---|---|
| AbstractList | To improve the existing light-addressable electrode (LAE) for neuronal stimulation, we attempted to replace a photoconductive layer of hydrogenated amorphous silicon (a-Si:H), which is subject to corrosion in cell culture environments, with a TiO2 nanocrystalline film. As seen in previous LAEs with a-Si:H, the TiO2 film formed on a metal film electrode serves as a photo-switch: UV light illumination locally increases the conductivity of the TiO2 film and generates a virtual electrode. TiO2 is a lower cost material, easier to fabricate than a-Si:H, and more compatible with cell culture environments; thus, it does not require a passivation layer on top. The measurements of photoelectric characteristics of TiO2 LAE ascertained that adequate photo-switching properties for selective neuronal stimulation were achieved; however, two possible issues that could affect performance were identified: degradation of the photo-switching property due to electrolyte penetration into the TiO2 film and a slow switching response due to charge carrier trapping into surface defects. Despite these issues, however, the feasibility of light-addressed electrical stimulation with the proposed TiO2 LAE was successfully demonstrated in an experiment using a primary neuron-glia co-culture. Thus, TiO2 is an alternative candidate to a-Si:H in photo-electrochemical biointerfaces. |
| Author | Takahashi, Hirokazu Jimbo, Yasuhiko Kanzaki, Ryohei Suzurikawa, Jun Nakao, Masayuki |
| Author_xml | – sequence: 1 givenname: Jun surname: Suzurikawa fullname: Suzurikawa, Jun email: suzurikawa-jun@rehab.go.jp organization: Department of Assistive Technology, Research Institute of National Rehabilitation Center for Persons with Disabilities, 4-1, Namiki, Tokorozawa-shi, Saitama 359-8555, Japan – sequence: 2 givenname: Masayuki surname: Nakao fullname: Nakao, Masayuki organization: Graduate School of Engineering, The University of Tokyo, 8-3-1, Hongo, Bunkyo-ku, Tokyo 113-8656, Japan – sequence: 3 givenname: Yasuhiko surname: Jimbo fullname: Jimbo, Yasuhiko organization: Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5, Kashiwanoha, Kashiwa-shi, Chiba 277-8563, Japan – sequence: 4 givenname: Ryohei surname: Kanzaki fullname: Kanzaki, Ryohei organization: Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1, Komaba, Meguro-ku, Tokyo 153-8904, Japan – sequence: 5 givenname: Hirokazu surname: Takahashi fullname: Takahashi, Hirokazu email: takahashi@i.u-tokyo.ac.jp organization: PRESTO, JST, 4-1-8, Honcho, Kawaguchi-shi, Saitama 332-0012, Japan |
| BookMark | eNqNkT1PHDEQhi1EpByEH5DOZZq9jNfr9a5SIZQvCYmG1JY_xuCTzwbbG0R-ffY4qhQo1WhG7zOaed8zcppyQkI-MtgyYOPn3bYms-2B8e1hxOcTsmGT5B0HKU_JBuZedAOAeE_Oat0BwMBH2JCnSxrD3X2j2rmCtWoTkWJE20p2SJ9Cu6ea3oabniadsi3PtekYQ0LqQ9xTnwuN2eoY_qB7BcPa0trCfom6hZxo9tQusS1llSRcSk71A3nndax48VrPya9vX2-vfnTXN99_Xl1ed3Y9tnWTdBP2xgvTezH0o8fRCK4NGOcHKRxoOephmoUYZ-2E0E7OIKwBlIb7YeDn5NNx70PJjwvWpvahWoxRJ8xLVWyaAPgwT_1_SMeJs1Gyg1QepbbkWgt6ZUN7-bUVHaJioA6pqJ1aU1GHVF5GfF5J9g_5UMJel-c3mS9HBlejfgcsqtqAyaILZfVbuRzeoP8CwNSpTQ |
| CitedBy_id | crossref_primary_10_3762_bjnano_13_15 crossref_primary_10_1016_j_coelec_2021_100727 crossref_primary_10_1016_j_bios_2022_115024 crossref_primary_10_1049_bsbt_2019_0045 crossref_primary_10_3390_s19204386 crossref_primary_10_1039_D2RA00282E crossref_primary_10_1002_pssa_201800150 crossref_primary_10_1021_acssensors_3c02712 crossref_primary_10_1021_acsami_2c21649 crossref_primary_10_1039_C7CS00860K crossref_primary_10_3390_bios11060171 crossref_primary_10_1002_elan_202100187 crossref_primary_10_1002_adma_201403513 crossref_primary_10_1039_C6TB01129B crossref_primary_10_1021_acs_analchem_9b00304 crossref_primary_10_3390_chemosensors10050156 crossref_primary_10_1039_D2CS00830K crossref_primary_10_3390_s20061680 crossref_primary_10_1016_j_snb_2014_11_150 crossref_primary_10_1021_acssensors_2c00940 crossref_primary_10_1021_acs_analchem_7b01898 crossref_primary_10_3390_s150409563 crossref_primary_10_1016_j_snb_2021_130422 crossref_primary_10_1021_acs_analchem_8b02244 |
| Cites_doi | 10.1109/TBME.2002.805470 10.1143/JJAP.44.8269 10.1039/b505718c 10.1016/0165-0270(93)90001-8 10.1111/j.1151-2916.1997.tb03245.x 10.1109/10.238465 10.1016/S0925-4005(01)00646-3 10.1143/JJAP.33.L394 10.1016/S0092-8674(01)00579-7 10.1109/JSSC.2004.837082 10.1126/science.3375810 10.1103/PhysRevLett.75.1670 10.1002/cphc.200600664 10.1039/b201230h 10.1109/JSSC.2003.819174 10.1016/j.jneumeth.2004.03.005 10.1038/nature03831 10.1016/0250-6874(81)80006-6 10.1039/B811740C 10.1063/1.2709627 10.1021/jp061346k 10.1016/j.tsf.2004.12.005 10.1557/mrs2000.151 10.1109/TBME.2009.2024314 10.1021/jp983386x 10.1016/j.snb.2010.03.048 10.1039/C0LC00117A 10.1016/S0956-5663(01)00135-X 10.1021/jp0707384 10.1016/j.biomaterials.2006.01.056 10.1073/pnas.0509881103 10.1039/b821678a 10.1021/jp073056p 10.1152/jn.00836.2004 10.1002/tee.20674 10.1016/j.snb.2010.05.058 10.1016/j.snb.2012.10.054 10.3390/s41000163 10.1088/0957-4484/18/36/365709 10.1016/j.ymeth.2005.05.020 |
| ContentType | Journal Article |
| Copyright | 2013 Elsevier B.V. |
| Copyright_xml | – notice: 2013 Elsevier B.V. |
| DBID | AAYXX CITATION 7TK 7SE 7SP 7SR 7TB 7U5 8BQ 8FD FR3 JG9 L7M |
| DOI | 10.1016/j.snb.2013.10.139 |
| DatabaseName | CrossRef Neurosciences Abstracts Corrosion Abstracts Electronics & Communications Abstracts Engineered Materials Abstracts Mechanical & Transportation Engineering Abstracts Solid State and Superconductivity Abstracts METADEX Technology Research Database Engineering Research Database Materials Research Database Advanced Technologies Database with Aerospace |
| DatabaseTitle | CrossRef Neurosciences Abstracts Materials Research Database Engineered Materials Abstracts Technology Research Database Mechanical & Transportation Engineering Abstracts Electronics & Communications Abstracts Solid State and Superconductivity Abstracts Engineering Research Database Corrosion Abstracts Advanced Technologies Database with Aerospace METADEX |
| DatabaseTitleList | Neurosciences Abstracts Materials Research Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Engineering |
| EISSN | 1873-3077 |
| EndPage | 398 |
| ExternalDocumentID | 10_1016_j_snb_2013_10_139 S0925400513013415 |
| GroupedDBID | --K --M -~X .~1 0R~ 123 1B1 1RT 1~. 1~5 4.4 457 4G. 53G 5VS 7-5 71M 8P~ 9JN AABNK AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AARLI AAXUO ABFNM ABMAC ABXDB ABYKQ ACDAQ ACGFS ACRLP ADBBV ADECG ADEZE ADTZH AEBSH AECPX AEKER AFKWA AFTJW AFZHZ AGHFR AGUBO AGYEJ AHHHB AHJVU AIEXJ AIKHN AITUG AJBFU AJOXV AJSZI ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ AXJTR BJAXD BKOJK BLXMC CS3 EBS EFJIC EFLBG EO8 EO9 EP2 EP3 F5P FDB FIRID FLBIZ FNPLU FYGXN G-Q GBLVA IHE J1W JJJVA KOM M36 M41 MO0 N9A O-L O9- OAUVE OZT P-8 P-9 PC. Q38 RIG RNS ROL RPZ SCC SDF SDG SDP SES SPC SPCBC SSK SST SSZ T5K TN5 YK3 ~G- AAQXK AATTM AAXKI AAYWO AAYXX ABWVN ACLOT ACNNM ACRPL ADMUD ADNMO AEIPS AFJKZ AGQPQ AIIUN AJQLL ANKPU APXCP ASPBG AVWKF AZFZN CITATION EFKBS EJD FEDTE FGOYB HMU HVGLF HZ~ R2- SCB SCH SEW WUQ ~HD 7TK 7SE 7SP 7SR 7TB 7U5 8BQ 8FD FR3 JG9 L7M |
| ID | FETCH-LOGICAL-c400t-87d8e2bf5b2f5426fe6b53ab0bdf475d0a76a4895569ad55ad7905cb0e7b3f443 |
| IEDL.DBID | .~1 |
| ISSN | 0925-4005 |
| IngestDate | Sun Sep 28 11:41:53 EDT 2025 Mon Sep 29 03:27:27 EDT 2025 Thu Apr 24 22:51:41 EDT 2025 Wed Oct 01 03:39:56 EDT 2025 Fri Feb 23 02:29:21 EST 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Keywords | Electrical stimulation Light-addressable electrode Neuron LAPS TiO2 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c400t-87d8e2bf5b2f5426fe6b53ab0bdf475d0a76a4895569ad55ad7905cb0e7b3f443 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| PQID | 1868316712 |
| PQPubID | 23462 |
| PageCount | 6 |
| ParticipantIDs | proquest_miscellaneous_1880034982 proquest_miscellaneous_1868316712 crossref_citationtrail_10_1016_j_snb_2013_10_139 crossref_primary_10_1016_j_snb_2013_10_139 elsevier_sciencedirect_doi_10_1016_j_snb_2013_10_139 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2014-03-01 |
| PublicationDateYYYYMMDD | 2014-03-01 |
| PublicationDate_xml | – month: 03 year: 2014 text: 2014-03-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationTitle | Sensors and actuators. B, Chemical |
| PublicationYear | 2014 |
| Publisher | Elsevier B.V |
| Publisher_xml | – name: Elsevier B.V |
| References | Hwang, Park (bib0070) 2009; 9 Eversmann, Jenkner, Hofmann, Paulus, Brederlow, Holzapfl, Fromherz, Merz, Brenner, Schreiter, Gabl, Plehnert, Steinhauser, Eckstein, Schmitt-Landsiedel, Thewes (bib0120) 2003; 38 Hafeman, Parce, McConnell (bib0005) 1988; 240 Wagenaar, Pine, Potter (bib0165) 2004; 138 Sinha, Hader (bib0195) 2002; 1 Hashimoto, Irie, Fujishima (bib0140) 2005; 44 Hwang, Park (bib0075) 2010; 11 Suzurikawa, Takahashi, Kanzaki, Nakao, Takayama, Jimbo (bib0015) 2007; 90 Colicos, Collins, Sailor, Goda (bib0010) 2001; 107 Fujihara, Kumar, Jose, Ramakrishna, Uchida (bib0145) 2007; 18 Jenkner, Tartagni, Hierlemann, Thewes, Res, AG, Munich (bib0100) 2004; 39 Pomoni, Vomvas, Trapalis (bib0130) 2005; 479 Suzurikawa, Nakao, Kanzaki, Takahashi (bib0050) 2010; 149 Suzurikawa, Nakao, Jimbo, Kanzaki, Takahashi (bib0090) 2009; 56 Yoshinobu, Iwasaki, Ui, Furuichi, Ermolenko, Mourzina, Wagner, Näther, Schöning (bib0045) 2005; 37 Chiou, Ohta, Wu (bib0065) 2005; 436 Xia, Masaki, Jiang, Yanagida (bib0185) 2007; 111 Suzurikawa, Nakao, Takahashi (bib0105) 2011; 6 Carbone, Marangi, Zanardi, Giorgetti, Chierici, Berlanda, Podestà, Fiorentini, Bongiorno, Piseri, Pelicci, Milani (bib0115) 2006; 27 O’Regan, Durrant, Sommeling, Bakker (bib0155) 2007; 111 Starovoytov, Choi, Seung (bib0085) 2005; 93 Bucher, Brunner, Leibrock, Schubert, Nisch (bib0080) 2001; 16 Hafeman, Harkins, Witkowski, Lewis, Warmack, Brown, Thundat (bib0060) 2006; 103 Matsuo, Esashi (bib0095) 1981; 1 Jimbo, Robinson, Kawana (bib1170) 1993; 40 Zhang (bib0125) 2013; 176 Ito, Liska, Comte, Charvet, Pechy, Bach, Schmidt-Mende, Zakeeruddin, Kay, Nazeeruddin (bib0190) 2005 Sommeling, O’Regan, Haswell, Smit, Bakker, Smits, Kroon, van Roosmalen (bib0160) 2006; 110 Yang, Li, Zhang, Li, Zhao (bib0180) 2010; 147 Zhao, Sheng, Zhai, Jiang, Yang, Sun, Li, Zhu (bib0150) 2007; 8 Yoshinobu, Ecken, Poghossian, Luth, Iwasaki, Schöning (bib0030) 2001; 76 Jimbo, Kasai, Torimitsu, Tateno, Robinson (bib0040) 2003; 50 Valley, Neale, Hsu, Ohta, Jamshidi, Wu (bib0055) 2009; 9 Fromherz, Stett (bib0110) 1995; 75 Gross, Rhoades, Reust, Schwalm (bib0035) 1993; 50 Gordon (bib0170) 2000; 25 Nakao, Yoshinobu, Iwasaki (bib0020) 1994; 33 Wang, Sakai, Fujishima, Watanabe, Hashimoto (bib0175) 1999; 103 Yoshinobu, Schöning, Finger, Moritz, Iwasaki (bib0025) 2004; 4 Barbe, Arendse, Comte, Jirousek, Lenzmann, Shklover, Gratzel (bib0135) 1997; 80 Gordon (10.1016/j.snb.2013.10.139_bib0170) 2000; 25 Hwang (10.1016/j.snb.2013.10.139_bib0075) 2010; 11 Eversmann (10.1016/j.snb.2013.10.139_bib0120) 2003; 38 Barbe (10.1016/j.snb.2013.10.139_bib0135) 1997; 80 Zhao (10.1016/j.snb.2013.10.139_bib0150) 2007; 8 Suzurikawa (10.1016/j.snb.2013.10.139_bib0015) 2007; 90 Hwang (10.1016/j.snb.2013.10.139_bib0070) 2009; 9 Hashimoto (10.1016/j.snb.2013.10.139_bib0140) 2005; 44 Carbone (10.1016/j.snb.2013.10.139_bib0115) 2006; 27 O’Regan (10.1016/j.snb.2013.10.139_bib0155) 2007; 111 Hafeman (10.1016/j.snb.2013.10.139_bib0005) 1988; 240 Zhang (10.1016/j.snb.2013.10.139_bib0125) 2013; 176 Fujihara (10.1016/j.snb.2013.10.139_bib0145) 2007; 18 Valley (10.1016/j.snb.2013.10.139_bib0055) 2009; 9 Nakao (10.1016/j.snb.2013.10.139_bib0020) 1994; 33 Jimbo (10.1016/j.snb.2013.10.139_bib0040) 2003; 50 Yang (10.1016/j.snb.2013.10.139_bib0180) 2010; 147 Sommeling (10.1016/j.snb.2013.10.139_bib0160) 2006; 110 Yoshinobu (10.1016/j.snb.2013.10.139_bib0030) 2001; 76 Matsuo (10.1016/j.snb.2013.10.139_bib0095) 1981; 1 Bucher (10.1016/j.snb.2013.10.139_bib0080) 2001; 16 Xia (10.1016/j.snb.2013.10.139_bib0185) 2007; 111 Colicos (10.1016/j.snb.2013.10.139_bib0010) 2001; 107 Sinha (10.1016/j.snb.2013.10.139_bib0195) 2002; 1 Suzurikawa (10.1016/j.snb.2013.10.139_bib0050) 2010; 149 Chiou (10.1016/j.snb.2013.10.139_bib0065) 2005; 436 Starovoytov (10.1016/j.snb.2013.10.139_bib0085) 2005; 93 Ito (10.1016/j.snb.2013.10.139_bib0190) 2005 Suzurikawa (10.1016/j.snb.2013.10.139_bib0090) 2009; 56 Jimbo (10.1016/j.snb.2013.10.139_bib1170) 1993; 40 Wagenaar (10.1016/j.snb.2013.10.139_bib0165) 2004; 138 Pomoni (10.1016/j.snb.2013.10.139_bib0130) 2005; 479 Hafeman (10.1016/j.snb.2013.10.139_bib0060) 2006; 103 Yoshinobu (10.1016/j.snb.2013.10.139_bib0025) 2004; 4 Jenkner (10.1016/j.snb.2013.10.139_bib0100) 2004; 39 Fromherz (10.1016/j.snb.2013.10.139_bib0110) 1995; 75 Gross (10.1016/j.snb.2013.10.139_bib0035) 1993; 50 Suzurikawa (10.1016/j.snb.2013.10.139_bib0105) 2011; 6 Wang (10.1016/j.snb.2013.10.139_bib0175) 1999; 103 Yoshinobu (10.1016/j.snb.2013.10.139_bib0045) 2005; 37 |
| References_xml | – volume: 149 start-page: 205 year: 2010 end-page: 211 ident: bib0050 article-title: Microscale pH gradient generation by electrolysis on a light-addressable planar electrode publication-title: Sens. Actuators B – volume: 4 start-page: 163 year: 2004 end-page: 169 ident: bib0025 article-title: Fabrication of thin-film LAPS with amorphous silicon publication-title: Sensors – volume: 90 start-page: 093901 year: 2007 ident: bib0015 article-title: Light-addressable electrode with hydrogenated amorphous silicon and low-conductive passivation layer for stimulation of cultured neurons publication-title: Appl. Phys. Lett. – volume: 16 start-page: 205 year: 2001 end-page: 210 ident: bib0080 article-title: Electrical properties of a light-addressable microelectrode chip with high electrode density for extracellular stimulation and recording of excitable cells publication-title: Biosens. Bioelectron. – volume: 25 start-page: 52 year: 2000 end-page: 57 ident: bib0170 article-title: Criteria for choosing transparent conductors publication-title: MRS Bull. – volume: 75 start-page: 1670 year: 1995 end-page: 1673 ident: bib0110 article-title: Silicon-neuron junction: capacitive stimulation of an individual neuron on a silicon chip publication-title: Phys. Rev. Lett. – volume: 50 start-page: 241 year: 2003 end-page: 248 ident: bib0040 article-title: A system for MEA-based multisite stimulation publication-title: IEEE Trans. Biomed. Eng. – volume: 39 start-page: 2431 year: 2004 end-page: 2437 ident: bib0100 article-title: Cell-based CMOS sensor and actuator arrays publication-title: IEEE J. Solid-State Circuits – volume: 37 start-page: 94 year: 2005 end-page: 102 ident: bib0045 article-title: The light-addressable potentiometric sensor for multi-ion sensing and imaging publication-title: Methods – volume: 176 start-page: 386 year: 2013 end-page: 389 ident: bib0125 article-title: High-performance impedimetric genosensor based on biocompatible TiO publication-title: Sens. Actuators B – volume: 103 start-page: 2188 year: 1999 end-page: 2194 ident: bib0175 article-title: Studies of surface wettability conversion on TiO publication-title: J. Phys. Chem. B – volume: 1 start-page: 225 year: 2002 end-page: 236 ident: bib0195 article-title: UV-induced DNA damage and repair: a review publication-title: Photochem. Photobiol. Sci. – volume: 103 start-page: 6436 year: 2006 end-page: 6441 ident: bib0060 article-title: Optically directed molecular transport and 3D isoelectric positioning of amphoteric biomolecules publication-title: Proc. Natl. Acad. Sci. U.S.A. – volume: 479 start-page: 160 year: 2005 end-page: 165 ident: bib0130 article-title: Transient photoconductivity of nanocrystalline TiO publication-title: Thin Solid Films – volume: 50 start-page: 131 year: 1993 end-page: 143 ident: bib0035 article-title: Stimulation of monolayer networks in culture through thin-film indium-tin oxide recording electrodes publication-title: J. Neurosci. Methods – volume: 1 start-page: 77 year: 1981 end-page: 96 ident: bib0095 article-title: Methods of ISFET fabrication publication-title: Sens. Actuators – volume: 138 start-page: 27 year: 2004 end-page: 37 ident: bib0165 article-title: Effective parameters for stimulation of dissociated cultures using multi-electrode arrays publication-title: J. Neurosci. Methods – volume: 40 start-page: 804 year: 1993 end-page: 810 ident: bib1170 article-title: Simultaneous measurement of intracellular calcium and electrical activity from patterned neural networks in culture publication-title: IEEE Trans. Biomed. Eng. – volume: 33 start-page: 394 year: 1994 end-page: 397 ident: bib0020 article-title: Improvement of spatial resolution of a laser-scanning pH-imaging sensor publication-title: Jpn. J. Appl. Phys. – volume: 110 start-page: 19191 year: 2006 end-page: 19197 ident: bib0160 article-title: Influence of a TiCl publication-title: J. Phys. Chem. B – volume: 93 start-page: 1090 year: 2005 end-page: 1098 ident: bib0085 article-title: Light-directed electrical stimulation of neurons cultured on silicon wafers publication-title: J. Neurophysiol. – volume: 240 start-page: 1182 year: 1988 end-page: 1185 ident: bib0005 article-title: Light-addressable potentiometric sensor for biochemical systems publication-title: Science – volume: 44 start-page: 8269 year: 2005 end-page: 8285 ident: bib0140 article-title: TiO publication-title: Jpn. J. Appl. Phys. – volume: 9 start-page: 199 year: 2009 end-page: 206 ident: bib0070 article-title: Rapid and selective concentration of microparticles in an optoelectrofluidic platform publication-title: Lab Chip – volume: 80 start-page: 3157 year: 1997 end-page: 3171 ident: bib0135 article-title: Nanocrystalline titanium oxide electrodes for photovoltaic applications publication-title: J. Am. Ceram. Soc. – volume: 9 start-page: 1714 year: 2009 end-page: 1720 ident: bib0055 article-title: Parallel single-cell light-induced electroporation and dielectrophoretic manipulation publication-title: Lab Chip – volume: 18 start-page: 365709 year: 2007 ident: bib0145 article-title: Spray deposition of electrospun TiO publication-title: Nanotechnology – volume: 111 start-page: 8092 year: 2007 end-page: 8097 ident: bib0185 article-title: Sputtered Nb publication-title: J. Phys. Chem. C – volume: 436 start-page: 370 year: 2005 end-page: 372 ident: bib0065 article-title: Massively parallel manipulation of single cells and microparticles using optical images publication-title: Nature – volume: 111 start-page: 14001 year: 2007 end-page: 14011 ident: bib0155 article-title: Influence of the TiCl publication-title: J Phys. Chem. C – volume: 11 start-page: 33 year: 2010 end-page: 47 ident: bib0075 article-title: Optoelectrofluidic platforms for chemistry and biology publication-title: Lab Chip – volume: 6 start-page: 392 year: 2011 end-page: 393 ident: bib0105 article-title: Surface passivation of the thin-film LAPS with perhydropolysilazane-derived silica treated by O publication-title: IEEJ Trans. Electr. Electron. Eng. – volume: 76 start-page: 388 year: 2001 end-page: 392 ident: bib0030 article-title: Alternative sensor materials for light-addressable potentiometric sensors publication-title: Sens. Actuators B – volume: 107 start-page: 605 year: 2001 end-page: 616 ident: bib0010 article-title: Remodeling of synaptic actin induced by photoconductive stimulation publication-title: Cell – volume: 8 start-page: 856 year: 2007 end-page: 861 ident: bib0150 article-title: TiO publication-title: ChemPhysChem – volume: 147 start-page: 622 year: 2010 end-page: 628 ident: bib0180 article-title: Preparation, characterization and sensing application of inkjet-printed nanostructured TiO publication-title: Sens. Actuators B – volume: 27 start-page: 3221 year: 2006 end-page: 3229 ident: bib0115 article-title: Biocompatibility of cluster-assembled nanostructured TiO publication-title: Biomaterials – start-page: 4351 year: 2005 end-page: 4353 ident: bib0190 article-title: Control of dark current in photoelectrochemical (TiO publication-title: Chem. Commun. – volume: 56 start-page: 2660 year: 2009 end-page: 2665 ident: bib0090 article-title: Light-addressed stimulation under Ca publication-title: IEEE Trans. Biomed. Eng. – volume: 38 start-page: 2306 year: 2003 end-page: 2317 ident: bib0120 article-title: A 128 publication-title: IEEE J. Solid-State Circuits – volume: 50 start-page: 241 year: 2003 ident: 10.1016/j.snb.2013.10.139_bib0040 article-title: A system for MEA-based multisite stimulation publication-title: IEEE Trans. Biomed. Eng. doi: 10.1109/TBME.2002.805470 – volume: 44 start-page: 8269 year: 2005 ident: 10.1016/j.snb.2013.10.139_bib0140 article-title: TiO2 photocatalysis: a historical overview and future prospects publication-title: Jpn. J. Appl. Phys. doi: 10.1143/JJAP.44.8269 – start-page: 4351 year: 2005 ident: 10.1016/j.snb.2013.10.139_bib0190 article-title: Control of dark current in photoelectrochemical (TiO2/I–I3−) and dye-sensitized solar cells publication-title: Chem. Commun. doi: 10.1039/b505718c – volume: 50 start-page: 131 year: 1993 ident: 10.1016/j.snb.2013.10.139_bib0035 article-title: Stimulation of monolayer networks in culture through thin-film indium-tin oxide recording electrodes publication-title: J. Neurosci. Methods doi: 10.1016/0165-0270(93)90001-8 – volume: 80 start-page: 3157 year: 1997 ident: 10.1016/j.snb.2013.10.139_bib0135 article-title: Nanocrystalline titanium oxide electrodes for photovoltaic applications publication-title: J. Am. Ceram. Soc. doi: 10.1111/j.1151-2916.1997.tb03245.x – volume: 40 start-page: 804 year: 1993 ident: 10.1016/j.snb.2013.10.139_bib1170 article-title: Simultaneous measurement of intracellular calcium and electrical activity from patterned neural networks in culture publication-title: IEEE Trans. Biomed. Eng. doi: 10.1109/10.238465 – volume: 76 start-page: 388 year: 2001 ident: 10.1016/j.snb.2013.10.139_bib0030 article-title: Alternative sensor materials for light-addressable potentiometric sensors publication-title: Sens. Actuators B doi: 10.1016/S0925-4005(01)00646-3 – volume: 33 start-page: 394 year: 1994 ident: 10.1016/j.snb.2013.10.139_bib0020 article-title: Improvement of spatial resolution of a laser-scanning pH-imaging sensor publication-title: Jpn. J. Appl. Phys. doi: 10.1143/JJAP.33.L394 – volume: 107 start-page: 605 year: 2001 ident: 10.1016/j.snb.2013.10.139_bib0010 article-title: Remodeling of synaptic actin induced by photoconductive stimulation publication-title: Cell doi: 10.1016/S0092-8674(01)00579-7 – volume: 39 start-page: 2431 year: 2004 ident: 10.1016/j.snb.2013.10.139_bib0100 article-title: Cell-based CMOS sensor and actuator arrays publication-title: IEEE J. Solid-State Circuits doi: 10.1109/JSSC.2004.837082 – volume: 240 start-page: 1182 year: 1988 ident: 10.1016/j.snb.2013.10.139_bib0005 article-title: Light-addressable potentiometric sensor for biochemical systems publication-title: Science doi: 10.1126/science.3375810 – volume: 75 start-page: 1670 year: 1995 ident: 10.1016/j.snb.2013.10.139_bib0110 article-title: Silicon-neuron junction: capacitive stimulation of an individual neuron on a silicon chip publication-title: Phys. Rev. Lett. doi: 10.1103/PhysRevLett.75.1670 – volume: 8 start-page: 856 year: 2007 ident: 10.1016/j.snb.2013.10.139_bib0150 article-title: TiO2 porous electrodes with hierarchical branched inner channels for charge transport in viscous electrolytes publication-title: ChemPhysChem doi: 10.1002/cphc.200600664 – volume: 1 start-page: 225 year: 2002 ident: 10.1016/j.snb.2013.10.139_bib0195 article-title: UV-induced DNA damage and repair: a review publication-title: Photochem. Photobiol. Sci. doi: 10.1039/b201230h – volume: 38 start-page: 2306 year: 2003 ident: 10.1016/j.snb.2013.10.139_bib0120 article-title: A 128×128 CMOS biosensor array for extracellular recording of neural activity publication-title: IEEE J. Solid-State Circuits doi: 10.1109/JSSC.2003.819174 – volume: 138 start-page: 27 year: 2004 ident: 10.1016/j.snb.2013.10.139_bib0165 article-title: Effective parameters for stimulation of dissociated cultures using multi-electrode arrays publication-title: J. Neurosci. Methods doi: 10.1016/j.jneumeth.2004.03.005 – volume: 436 start-page: 370 year: 2005 ident: 10.1016/j.snb.2013.10.139_bib0065 article-title: Massively parallel manipulation of single cells and microparticles using optical images publication-title: Nature doi: 10.1038/nature03831 – volume: 1 start-page: 77 year: 1981 ident: 10.1016/j.snb.2013.10.139_bib0095 article-title: Methods of ISFET fabrication publication-title: Sens. Actuators doi: 10.1016/0250-6874(81)80006-6 – volume: 9 start-page: 199 year: 2009 ident: 10.1016/j.snb.2013.10.139_bib0070 article-title: Rapid and selective concentration of microparticles in an optoelectrofluidic platform publication-title: Lab Chip doi: 10.1039/B811740C – volume: 90 start-page: 093901 year: 2007 ident: 10.1016/j.snb.2013.10.139_bib0015 article-title: Light-addressable electrode with hydrogenated amorphous silicon and low-conductive passivation layer for stimulation of cultured neurons publication-title: Appl. Phys. Lett. doi: 10.1063/1.2709627 – volume: 110 start-page: 19191 year: 2006 ident: 10.1016/j.snb.2013.10.139_bib0160 article-title: Influence of a TiCl4 post-treatment on nanocrystalline TiO2 films in dye-sensitized solar cells publication-title: J. Phys. Chem. B doi: 10.1021/jp061346k – volume: 479 start-page: 160 year: 2005 ident: 10.1016/j.snb.2013.10.139_bib0130 article-title: Transient photoconductivity of nanocrystalline TiO2 sol–gel thin films publication-title: Thin Solid Films doi: 10.1016/j.tsf.2004.12.005 – volume: 25 start-page: 52 year: 2000 ident: 10.1016/j.snb.2013.10.139_bib0170 article-title: Criteria for choosing transparent conductors publication-title: MRS Bull. doi: 10.1557/mrs2000.151 – volume: 56 start-page: 2660 year: 2009 ident: 10.1016/j.snb.2013.10.139_bib0090 article-title: Light-addressed stimulation under Ca2+ imaging of cultured neurons publication-title: IEEE Trans. Biomed. Eng. doi: 10.1109/TBME.2009.2024314 – volume: 103 start-page: 2188 year: 1999 ident: 10.1016/j.snb.2013.10.139_bib0175 article-title: Studies of surface wettability conversion on TiO2 single-crystal surfaces publication-title: J. Phys. Chem. B doi: 10.1021/jp983386x – volume: 147 start-page: 622 year: 2010 ident: 10.1016/j.snb.2013.10.139_bib0180 article-title: Preparation, characterization and sensing application of inkjet-printed nanostructured TiO2 photoanode publication-title: Sens. Actuators B doi: 10.1016/j.snb.2010.03.048 – volume: 11 start-page: 33 year: 2010 ident: 10.1016/j.snb.2013.10.139_bib0075 article-title: Optoelectrofluidic platforms for chemistry and biology publication-title: Lab Chip doi: 10.1039/C0LC00117A – volume: 16 start-page: 205 year: 2001 ident: 10.1016/j.snb.2013.10.139_bib0080 article-title: Electrical properties of a light-addressable microelectrode chip with high electrode density for extracellular stimulation and recording of excitable cells publication-title: Biosens. Bioelectron. doi: 10.1016/S0956-5663(01)00135-X – volume: 111 start-page: 8092 year: 2007 ident: 10.1016/j.snb.2013.10.139_bib0185 article-title: Sputtered Nb2O5 as a novel blocking layer at conducting glass/TiO2 interfaces in dye-sensitized ionic liquid solar cells publication-title: J. Phys. Chem. C doi: 10.1021/jp0707384 – volume: 27 start-page: 3221 year: 2006 ident: 10.1016/j.snb.2013.10.139_bib0115 article-title: Biocompatibility of cluster-assembled nanostructured TiO2 with primary and cancer cells publication-title: Biomaterials doi: 10.1016/j.biomaterials.2006.01.056 – volume: 103 start-page: 6436 year: 2006 ident: 10.1016/j.snb.2013.10.139_bib0060 article-title: Optically directed molecular transport and 3D isoelectric positioning of amphoteric biomolecules publication-title: Proc. Natl. Acad. Sci. U.S.A. doi: 10.1073/pnas.0509881103 – volume: 9 start-page: 1714 year: 2009 ident: 10.1016/j.snb.2013.10.139_bib0055 article-title: Parallel single-cell light-induced electroporation and dielectrophoretic manipulation publication-title: Lab Chip doi: 10.1039/b821678a – volume: 111 start-page: 14001 year: 2007 ident: 10.1016/j.snb.2013.10.139_bib0155 article-title: Influence of the TiCl4 treatment on nanocrystalline TiO2 films in dye-sensitized solar cells 2 charge density, band edge shifts, and quantification of recombination losses at short circuit publication-title: J Phys. Chem. C doi: 10.1021/jp073056p – volume: 93 start-page: 1090 year: 2005 ident: 10.1016/j.snb.2013.10.139_bib0085 article-title: Light-directed electrical stimulation of neurons cultured on silicon wafers publication-title: J. Neurophysiol. doi: 10.1152/jn.00836.2004 – volume: 6 start-page: 392 year: 2011 ident: 10.1016/j.snb.2013.10.139_bib0105 article-title: Surface passivation of the thin-film LAPS with perhydropolysilazane-derived silica treated by O2 plasma publication-title: IEEJ Trans. Electr. Electron. Eng. doi: 10.1002/tee.20674 – volume: 149 start-page: 205 year: 2010 ident: 10.1016/j.snb.2013.10.139_bib0050 article-title: Microscale pH gradient generation by electrolysis on a light-addressable planar electrode publication-title: Sens. Actuators B doi: 10.1016/j.snb.2010.05.058 – volume: 176 start-page: 386 year: 2013 ident: 10.1016/j.snb.2013.10.139_bib0125 article-title: High-performance impedimetric genosensor based on biocompatible TiO2 nanoparticles supported carbon ionic liquid electrode publication-title: Sens. Actuators B doi: 10.1016/j.snb.2012.10.054 – volume: 4 start-page: 163 year: 2004 ident: 10.1016/j.snb.2013.10.139_bib0025 article-title: Fabrication of thin-film LAPS with amorphous silicon publication-title: Sensors doi: 10.3390/s41000163 – volume: 18 start-page: 365709 year: 2007 ident: 10.1016/j.snb.2013.10.139_bib0145 article-title: Spray deposition of electrospun TiO2 nanorods for dye-sensitized solar cell publication-title: Nanotechnology doi: 10.1088/0957-4484/18/36/365709 – volume: 37 start-page: 94 year: 2005 ident: 10.1016/j.snb.2013.10.139_bib0045 article-title: The light-addressable potentiometric sensor for multi-ion sensing and imaging publication-title: Methods doi: 10.1016/j.ymeth.2005.05.020 |
| SSID | ssj0004360 |
| Score | 2.2388515 |
| Snippet | To improve the existing light-addressable electrode (LAE) for neuronal stimulation, we attempted to replace a photoconductive layer of hydrogenated amorphous... |
| SourceID | proquest crossref elsevier |
| SourceType | Aggregation Database Enrichment Source Index Database Publisher |
| StartPage | 393 |
| SubjectTerms | Biomaterials Biotechnology Electrical stimulation Electrodes Illumination LAPS Light-addressable electrode Nanocrystals Neuron Stimulation TiO2 Titanium dioxide Trapping |
| Title | A light addressable electrode with a TiO2 nanocrystalline film for localized electrical stimulation of cultured neurons |
| URI | https://dx.doi.org/10.1016/j.snb.2013.10.139 https://www.proquest.com/docview/1868316712 https://www.proquest.com/docview/1880034982 |
| Volume | 192 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVESC databaseName: Baden-Württemberg Complete Freedom Collection (Elsevier) customDbUrl: eissn: 1873-3077 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0004360 issn: 0925-4005 databaseCode: GBLVA dateStart: 20110101 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier – providerCode: PRVESC databaseName: Elsevier ScienceDirect customDbUrl: eissn: 1873-3077 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0004360 issn: 0925-4005 databaseCode: .~1 dateStart: 19950101 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier – providerCode: PRVESC databaseName: Elsevier SD Complete Freedom Collection [SCCMFC] customDbUrl: eissn: 1873-3077 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0004360 issn: 0925-4005 databaseCode: ACRLP dateStart: 19950101 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier – providerCode: PRVESC databaseName: Elsevier SD Freedom Collection Journals [SCFCJ] customDbUrl: eissn: 1873-3077 dateEnd: 99991231 omitProxy: true ssIdentifier: ssj0004360 issn: 0925-4005 databaseCode: AIKHN dateStart: 19950101 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1NT9wwELUQvdADooWqy5eMxAkpu97EzjrHFSraFgEHQNpbZMdjKdWSRewi1B747cw4TkuRugeOscZK4pnMjOOZ9xg7FtobAVomPhMikVb6xIgqT8xQV16Asq6gbuSLy3xyK39M1XSNnXa9MFRWGX1_69ODt44jg7iag_u6HlyLAjc3ZFRoo1nbaE7oX2jT_ee_ZR4yC53CJJyQdHeyGWq8Fo2l6q6sHwggiv_FpjdeOoSesy22GXNGPm4f6xNbg-Yz-_gKSXCbPY35jLbZHB1JYDWxM-CR4sYBp7-t3PCb-irljWnm1cMvzAoJjhu4r2d3HFNXHsJa_RtcnEjq4-gB7iLDF5973gJ1oEjAwWwWO-z27NvN6SSJnApJhW-_ROfnNKTWK5t6hdHZQ25VZqywzsuRcsKMciN1oVReGKeUcYTgVVkBI5t5KbMvbL2ZN_CVcQBfaZFWI-FAemGtMRJS3CDpAgppXY-JbjXLKgKOE-_FrOwqy36WqICSFBCGsqLHTv5MuW_RNlYJy05F5T8mU2I0WDXtqFNniZ8SnY-YBuaPi5KYAwgYYJiuktEB0kenu--7_R7bwCvZlrHts_XlwyMcYF6ztIfBcA_Zh_H388nlCx9L-lE |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT-MwELZQOcAe0C4PLY_dNRInpFCT2KlzrNCiskA5UCRulh2PpaCSIlqE4NczdhxgkeiBq-NREs_km3E88w0he0w6zUDyxGWMJdxwl2hW5ok-lKVjIIwtfDXy-TAfXPF_1-J6gRy1tTA-rTJif4PpAa3jSDeuZveuqrqXrMDNjTcqtNEsFJovcoGY3CGL_ZPTwfCtPDILxcJ-fuIF2sPNkOY1rY1P8MoOQg-I4jP39AGog_c5_k5WYthI-82T_SALUK-Sb-_IBNfIY5-O_U6bIpaExiZmDDR2ubFA_Q9XqumoukhpretJef-EgaFn5AbqqvEtxeiVBs9WPYONgl6DFEHgNjb5ohNHG64OnBKoMOvpOrk6_js6GiSxrUJS4tvPEP-shNQ4YVIn0EE7yI3ItGHGOt4TlulerrkshMgLbYXQ1pN4lYZBz2SO82yDdOpJDT8JBXClZGnZYxa4Y8ZozSHFPZIsoODGbhLWrqYqI-e4b30xVm1y2Y1CBSivgDCUFZtk_1XkriHcmDeZtypS_1mNQocwT2y3VafCr8kfkegaJg9T5ZsHeG6Aw3TeHBlYfWS69bXb_yFLg9H5mTo7GZ5uk2W8wpusth3Smd0_wC8Mc2bmdzTjF5qw_Pw |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+light+addressable+electrode+with+a+TiO2+nanocrystalline+film+for+localized+electrical+stimulation+of+cultured+neurons&rft.jtitle=Sensors+and+actuators.+B%2C+Chemical&rft.au=Suzurikawa%2C+Jun&rft.au=Nakao%2C+Masayuki&rft.au=Jimbo%2C+Yasuhiko&rft.au=Kanzaki%2C+Ryohei&rft.date=2014-03-01&rft.pub=Elsevier+B.V&rft.issn=0925-4005&rft.eissn=1873-3077&rft.volume=192&rft.spage=393&rft.epage=398&rft_id=info:doi/10.1016%2Fj.snb.2013.10.139&rft.externalDocID=S0925400513013415 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0925-4005&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0925-4005&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0925-4005&client=summon |