Effect of solution viscosity on retardation of cell sedimentation in DLP 3D printing of gelatin methacrylate/silk fibroin bioink
[Display omitted] To improve the cell suspension of the gelatin-methacrylate(GelMA) bioink, the viscosity of the ink solution was controlled by biocompatible silk fibroin(SF) particles. The viscosity of the GelMA solution increased about 1.4 × 102 folds by the addition of 1 w/v% SF particles. The in...
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| Published in | Journal of industrial and engineering chemistry (Seoul, Korea) Vol. 61; pp. 340 - 347 |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Elsevier B.V
25.05.2018
한국공업화학회 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1226-086X 1876-794X |
| DOI | 10.1016/j.jiec.2017.12.032 |
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| Abstract | [Display omitted]
To improve the cell suspension of the gelatin-methacrylate(GelMA) bioink, the viscosity of the ink solution was controlled by biocompatible silk fibroin(SF) particles. The viscosity of the GelMA solution increased about 1.4 × 102 folds by the addition of 1 w/v% SF particles. The increase of solution viscosity reduced the displacement of cells and retarded the cell sedimentation significantly. SF-GelMA bioink containing 1 w/v% SF was non-cytotoxic and used for the 3D bioprinting by directly projecting a feature onto the bioink. The cells encapsulated in the structures showed a high level of metabolic activity and demonstrated that SF-GelMA was a biocompatible material. |
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| AbstractList | To improve the cell suspension of the gelatin-methacrylate(GelMA) bioink, the viscosity of the ink solution was controlled by biocompatible silk fibroin(SF) particles. The viscosity of the GelMA solution increased about 1.4 × 102 folds by the addition of 1 w/v% SF particles. The increase of solution viscosity reduced the displacement of cells and retarded the cell sedimentation significantly. SF-GelMA bioink containing 1 w/v% SF was non-cytotoxic and used for the 3D bioprinting by directly projecting a feature onto the bioink. The cells encapsulated in the structures showed a high level of metabolic activity and demonstrated that SF-GelMA was a biocompatible material. KCI Citation Count: 58 [Display omitted] To improve the cell suspension of the gelatin-methacrylate(GelMA) bioink, the viscosity of the ink solution was controlled by biocompatible silk fibroin(SF) particles. The viscosity of the GelMA solution increased about 1.4 × 102 folds by the addition of 1 w/v% SF particles. The increase of solution viscosity reduced the displacement of cells and retarded the cell sedimentation significantly. SF-GelMA bioink containing 1 w/v% SF was non-cytotoxic and used for the 3D bioprinting by directly projecting a feature onto the bioink. The cells encapsulated in the structures showed a high level of metabolic activity and demonstrated that SF-GelMA was a biocompatible material. |
| Author | Shin, Donghyeok Baek, Jihye Shin, Jonghyun Park, Minsung Hyun, Jinho Kwak, Hojung Na, Kyunga Shin, Sungchul Lee, Hyunji |
| Author_xml | – sequence: 1 givenname: Kyunga surname: Na fullname: Na, Kyunga organization: Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Republic of Korea – sequence: 2 givenname: Sungchul surname: Shin fullname: Shin, Sungchul organization: Department of Biosystems and Biomaterials Science and Engineering, Seoul National University, Seoul 08826, Republic of Korea – sequence: 3 givenname: Hyunji surname: Lee fullname: Lee, Hyunji organization: Department of Biosystems and Biomaterials Science and Engineering, Seoul National University, Seoul 08826, Republic of Korea – sequence: 4 givenname: Donghyeok surname: Shin fullname: Shin, Donghyeok organization: Department of Biosystems and Biomaterials Science and Engineering, Seoul National University, Seoul 08826, Republic of Korea – sequence: 5 givenname: Jihye surname: Baek fullname: Baek, Jihye organization: Kukdong R&D Center, 135 Hasinbeonyeong-ro, Saha-gu, Busan 49432, Republic of Korea – sequence: 6 givenname: Hojung surname: Kwak fullname: Kwak, Hojung organization: Department of Biosystems and Biomaterials Science and Engineering, Seoul National University, Seoul 08826, Republic of Korea – sequence: 7 givenname: Minsung surname: Park fullname: Park, Minsung organization: Department of Biosystems and Biomaterials Science and Engineering, Seoul National University, Seoul 08826, Republic of Korea – sequence: 8 givenname: Jonghyun surname: Shin fullname: Shin, Jonghyun organization: Department of Biosystems and Biomaterials Science and Engineering, Seoul National University, Seoul 08826, Republic of Korea – sequence: 9 givenname: Jinho surname: Hyun fullname: Hyun, Jinho email: jhyun@snu.ac.kr organization: Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Republic of Korea |
| BackLink | https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002347484$$DAccess content in National Research Foundation of Korea (NRF) |
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| Keywords | Solution viscosity Silk fibroin particle Cell sedimentation Digital light processing (DLP) 3D printing Gelatin-methacrylate (GelMA) |
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To improve the cell suspension of the gelatin-methacrylate(GelMA) bioink, the viscosity of the ink solution was controlled by biocompatible... To improve the cell suspension of the gelatin-methacrylate(GelMA) bioink, the viscosity of the ink solution was controlled by biocompatible silk fibroin(SF)... |
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| StartPage | 340 |
| SubjectTerms | Cell sedimentation Digital light processing (DLP) 3D printing Gelatin-methacrylate (GelMA) Silk fibroin particle Solution viscosity 화학공학 |
| Title | Effect of solution viscosity on retardation of cell sedimentation in DLP 3D printing of gelatin methacrylate/silk fibroin bioink |
| URI | https://dx.doi.org/10.1016/j.jiec.2017.12.032 https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002347484 |
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| ispartofPNX | Journal of Industrial and Engineering Chemistry, 2018, 61(0), , pp.340-347 |
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