Case of pemphigoid with immunoglobulin G antibodies to BP180 C‐terminal domain and laminin‐γ1 (p200) developed after pneumococcal vaccination

• Published in: Journal of dermatology Vol. 48; no. 1; pp. 101 - 105
• Main Authors: Maki, Nobuki, Hashimoto, Takashi, Yamada, Tomoko, Ishii, Norito, Tsuruta, Daisuke, Demitsu, Toshio
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.01.2021
• Subjects: Adult; Aged; Autoantibodies; Autoantigens; BP180; Bullous pemphigoid; Case reports; Humans; Immunization; Immunoglobulin G; Immunoglobulins; Infants; Laminin; laminin‐γ1 (p200); Non-Fibrillar Collagens; Older people; pemphigoid disease; Pemphigoid, Bullous - chemically induced; Pemphigoid, Bullous - diagnosis; pneumococcal vaccination; Side effects; Skin diseases; trigger; Vaccination; pneumococcal vaccination; laminin-γ1 (p200); trigger; pemphigoid disease; BP180
• ISSN: 0385-2407; 1346-8138; 1346-8138
• DOI: 10.1111/1346-8138.15626

Pemphigoid cases have been reported in association with vaccination, including pneumococcal vaccination in infants but not in adults. There are also sporadic reports of pemphigoid diseases involving reactions to multiple autoantigens. We herein report a 75‐year‐old Japanese patient with pemphigoid who had immunoglobulin G antibodies to both the BP180 C‐terminal domain and laminin‐γ1 (p200), which developed 1 day after pneumococcal vaccination.