Immune Dysregulation and Endothelial Dysfunction in Pulmonary Arterial Hypertension: A Complex Interplay

• Published in: Circulation (New York, N.Y.) Vol. 129; no. 12; pp. 1332 - 1340
• Main Authors: Huertas, Alice, Perros, Frédéric, Tu, Ly, Cohen-Kaminsky, Sylvia, Montani, David, Dorfmüller, Peter, Guignabert, Christophe, Humbert, Marc
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD by the American College of Cardiology Foundation and the American Heart Association, Inc 25.03.2014; Lippincott Williams & Wilkins
• Subjects: Arterial hypertension. Arterial hypotension; Biological and medical sciences; Blood and lymphatic vessels; Cardiology. Vascular system; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Endothelium, Vascular - immunology; Endothelium, Vascular - physiopathology; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary - complications; Hypertension, Pulmonary - immunology; Hypertension, Pulmonary - physiopathology; Immune System Diseases - complications; Immune System Diseases - immunology; Immune System Diseases - physiopathology; Medical sciences; Pneumology; Pulmonary Artery - immunology; Pulmonary Artery - physiopathology; Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases; Vasculitis - complications; Vasculitis - immunology; Vasculitis - physiopathology; Autoimmunity; Hypertension; Immunopathology; Respiratory disease; Lung; Cardiovascular disease; pulmonary; Respiratory system; Complexes; Artery; Pulmonary hypertension; Complexity; Endothelium; Dysfunction; Blood vessel; Endothelial dysfunction; Circulatory system; Cardiology; Immune system; hypertension, pulmonary; immune system; endothelium; autoimmunity
• ISSN: 0009-7322; 1524-4539; 1524-4539
• DOI: 10.1161/CIRCULATIONAHA.113.004555