Comment on “The Geometric Structure of the Brain Fiber Pathways”

Wedeen et al . (Reports, 30 March 2012, p. 1628) proposed a geometrical grid pattern in the brain that could help the understanding of the brain’s organization and connectivity. We show that whole-brain fiber crossing quantification does not support their theory. Our results suggest that the grid pa...

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Bibliographic Details
Published inScience (American Association for the Advancement of Science) Vol. 337; no. 6102; p. 1605
Main Authors Catani, Marco, Bodi, Istvan, Dell’Acqua, Flavio
Format Journal Article
LanguageEnglish
Published United States The American Association for the Advancement of Science 28.09.2012
Subjects
Animals
Brain
Cerebral Cortex - anatomy & histology
Connectivity
Geometry
Humans
Nerve Fibers
Neural Pathways - anatomy & histology
Online AccessGet full text
ISSN0036-8075
1095-9203
1095-9203
DOI10.1126/science.1223425

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Summary:Wedeen et al . (Reports, 30 March 2012, p. 1628) proposed a geometrical grid pattern in the brain that could help the understanding of the brain’s organization and connectivity. We show that whole-brain fiber crossing quantification does not support their theory. Our results suggest that the grid pattern is most likely an artifact attributable to the limitations of their method.
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ISSN:0036-8075
1095-9203
1095-9203
DOI:10.1126/science.1223425