Impact Loading on a Patient-Specific Head Model: The Significance of Brain Constitutive Models and Loading Location

• Published in: Mathematical and computational applications Vol. 30; no. 2; p. 21
• Main Authors: Gandomirouzbahani, Amirhossein, Taghizadeh, Hadi, Oskui, Iman Z., Fernandes, Fábio A. O.
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.04.2025
• Subjects: Accuracy; Analysis; Brain; Cerebrospinal fluid; Constitutive models; deviatoric and volumetric response; finite element analysis; Geometry; Head injuries; hyper-viscoelastic constitutive modeling; Impact loads; Injuries; Investigations; Lateral loads; Mechanical properties; Mechanics; Medical research; Medicine, Experimental; Simulation; Strain energy; stress analysis; Tissues; Traumatic brain injury; Viscoelasticity
• ISSN: 2297-8747; 1300-686X; 2297-8747
• DOI: 10.3390/mca30020021

Head impacts are common incidents that may cause traumatic brain injury (TBI), which imposes significant economic and social burdens. This study developed a patient-specific head model to address the significance of the brain’s constitutive model and loading location on head impact. Two hyperelastic (Model I and Model II) constitutive models and one hyper-viscoelastic (Model III) constitutive model for the brain tissue were developed. In Models II and III, white and gray matter heterogeneities were included. Respective volumetric and deviatoric responses were compared for a frontal head impact. Then, the load was applied to the head’s frontal, lateral, and posterior regions to report location-wise outcomes. The findings indicated that Model I, which was based on almost quasi-static experiments, underestimated the deviatoric responses. Although the pressure contours were similar for Models II and III, the latter included viscous effects and provided more accurate deviatoric responses. Lateral loading indicated a significantly higher risk of TBI. Interestingly, the deviatoric responses and strain energy density of the brain did not decay with relaxation of the impact load. Hence, the incidence of TBI should be explored after load relaxation.