Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer

• Published in: The New England journal of medicine Vol. 386; no. 10; pp. 923 - 932
• Main Authors: Leboulleux, Sophie, Bournaud, Claire, Chougnet, Cecile N., Zerdoud, Slimane, Al Ghuzlan, Abir, Catargi, Bogdan, Do Cao, Christine, Kelly, Antony, Barge, Marie-Luce, Lacroix, Ludovic, Dygai, Inna, Vera, Pierre, Rusu, Daniela, Schneegans, Olivier, Benisvy, Danielle, Klein, Marc, Roux, Julie, Eberle, Marie-Claude, Bastie, Delphine, Nascimento, Camila, Giraudet, Anne-Laure, Le Moullec, Nathalie, Bardet, Stéphane, Drui, Delphine, Roudaut, Nathalie, Godbert, Yann, Morel, Olivier, Drutel, Anne, Lamartina, Livia, Schvartz, Claire, Velayoudom, Fritz-Line, Schlumberger, Martin-Jean, Leenhardt, Laurence, Borget, Isabelle
• Format: Journal Article
• Language: English
• Published: United States Massachusetts Medical Society 10.03.2022
• Subjects: Ablation; Adult; Antibodies; Combined Modality Therapy; Dissection; Endocrinology; Female; Follow-Up Studies; Hematology; Humans; Iodine; Iodine Radioisotopes - therapeutic use; Laboratories; Lymphatic system; Male; Medical prognosis; Middle Aged; Neck; Neck - diagnostic imaging; Oncology; Patients; Prognosis; Quality of Life; Radiology; Radiology General; Structure-function relationships; Surgery; Surgery General; Thyroglobulin; Thyroid cancer; Thyroid Disease; Thyroid Neoplasms - diagnostic imaging; Thyroid Neoplasms - radiotherapy; Thyroid Neoplasms - surgery; Thyroid-stimulating hormone; Thyroidectomy; Treatments in Oncology; Ultrasonic imaging; Ultrasonography
• ISSN: 0028-4793; 1533-4406; 1533-4406
• DOI: 10.1056/NEJMoa2111953

In this randomized phase 3 trial involving patients with low-risk differentiated thyroid cancer undergoing thyroidectomy, a follow-up strategy that did not involve the use of radioiodine was noninferior to the use of radioiodine in the response to treatment at 3 years.