Impact of COVID‐19 in solid organ transplant recipients

• Published in: American journal of transplantation Vol. 21; no. 3; pp. 925 - 937
• Main Authors: Danziger‐Isakov, Lara, Blumberg, Emily A., Manuel, Oriol, Sester, Martina
• Format: Journal Article
• Language: English
• Published: United States Elsevier Limited 01.03.2021
• Subjects: antibiotic: antiviral; Antibiotics; Antiviral drugs; Comorbidity; Coronaviridae; Coronaviruses; COVID-19; COVID-19 - epidemiology; Epidemiology; Health care; health services and outcomes research viewpoint; Humans; immunosuppression / immune modulation; infectious disease; organ procurement; Organ Transplantation - trends; organ transplantation in general; Pandemics; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Tissue and Organ Procurement - methods; Tissue Donors - supply & distribution; Transplant Recipients - statistics & numerical data; Transplantation; Transplants & implants; United infection and infectious agents ‐ viral; COVID-19; United infection and infectious agents - viral; immunosuppression / immune modulation; organ procurement; infectious disease; organ transplantation in general; health services and outcomes research viewpoint; antibiotic: antiviral
• ISSN: 1600-6135; 1600-6143; 1600-6143
• DOI: 10.1111/ajt.16449

The coronavirus disease 2019 (COVID‐19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) exploded onto the world stage in early 2020. The impact on solid organ transplantation (SOT) has been profound affecting potential donors, candidates, and recipients. Importantly, decreased donations and the pressure of limited resources placed on health care by the pandemic also disrupted transplant systems. We address the impact of COVID‐19 on organ transplantation globally and review current understanding of the epidemiology, outcomes, diagnosis, and treatment of COVID‐19 in SOT recipients. The authors address the global impact of COVID‐19 on organ transplantation and the current understanding of the epidemiology, outcomes, diagnosis, and treatment of COVID‐19 in solid organ transplant recipients.