Recent Advances in Pathology: the 2020 Annual Review Issue of The Journal of Pathology

• Published in: The Journal of pathology Vol. 250; no. 5; pp. 475 - 479
• Main Authors: Herrington, C Simon, Poulsom, Richard, Coates, Philip J
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.04.2020; Wiley Subscription Services, Inc
• Subjects: acute response; ageing; algorithm; anti‐sense lncRNA; Apoptosis; artificial intelligence; astrocytoma; Atherosclerosis; ATXN1L; autophagy; biologics; biomarker risk‐management; Brain cancer; Breast cancer; cancer predisposition; Capicua; Cdc42; CELSR1; chemotaxis; chronic inactive lesions; chronic kidney disease; clear cell renal cell carcinoma; clinical trial; clonogen; collective cell migration; Colorectal cancer; computational pathology; COPD; decision support; demyelinated lesions; development; diabetes; diagnosis; digital histology; DNA methylation profiling; DNA mismatch repair; durotaxis; ECM; Endometrial cancer; ependymoma; Epigenetics; Ewing's tumour; exosomes; foam cells; gene variant interpretation; Genetic disorders; genome‐wide association study; glioblastoma; glomerulonephritis; grey matter; HDAC; host‐directed therapy; hypoxia; hypoxia‐inducible factor; image analysis; immunity; immunoediting; immunotherapy; inflammation; inflammatory lesions; interleukin‐6; invasion; ionising radiation; Kidney cancer; late response; long intergenic non‐coding RNA; long non‐coding RNA; Lynch syndrome; macrophage; macropinocytosis; mass cytometry; medulloblastoma; Mendelian randomisation; Mesenchymal stem cells; mesenchymal stromal cells; metabolic disorders; metastasis; migration; miRNA; monocyte; multiple sclerosis; neoplasia; nephropathology; Neuroblastoma; neurodegenerative disease; neurogenesis; Oxidative stress; oxygen; Pathology; PD‐L1; personalised treatment; precision imaging; pseudohypoxia; Rac1; receptor; RhoA; RhoGTPase; scATACseq; senescence; sex differences; single‐cell RNAseq; small airways; stem cell; stem cells; SWI/SNF; TILs; tissue regeneration; Toll‐like receptors; translation; transplantation; TREM2; tuberculosis; tumour microenvironment; white matter; X chromosome inactivation; neuroblastoma; scATACseq; decision support; CELSR1; artificial intelligence; interleukin-6; late response; neoplasia; DNA mismatch repair; Mendelian randomisation; algorithm; chemotaxis; atherosclerosis; stem cells; autophagy; colorectal cancer; biologics; digital histology; tuberculosis; macrophage; Ewing's tumour; glioblastoma; mesenchymal stem cells; endometrial cancer; long non-coding RNA; tumour microenvironment; single-cell RNAseq; HDAC; chronic kidney disease; immunity; white matter; ionising radiation; astrocytoma; inflammation; metastasis; PD-L1; acute response; grey matter; miRNA; sex differences; durotaxis; clear cell renal cell carcinoma; computational pathology; multiple sclerosis; clonogen; cancer predisposition; Breast cancer; hypoxia-inducible factor; ECM; ependymoma; tissue regeneration; macropinocytosis; invasion; demyelinated lesions; monocyte; glomerulonephritis; diabetes; oxidative stress; COPD; long intergenic non-coding RNA; chronic inactive lesions; TREM2; image analysis; RhoGTPase; personalised treatment; senescence; SWI/SNF; neurogenesis; Rac1; small airways; DNA methylation profiling; oxygen; clinical trial; foam cells; hypoxia; metabolic disorders; development; medulloblastoma; diagnosis; RhoA; transplantation; collective cell migration; mass cytometry; immunoediting; neurodegenerative disease; mesenchymal stromal cells; apoptosis; biomarker risk-management; inflammatory lesions; stem cell; exosomes; ATXN1L; X chromosome inactivation; immunotherapy; Toll-like receptors; Cdc42; Lynch syndrome; nephropathology; ageing; pseudohypoxia; host-directed therapy; gene variant interpretation; anti-sense lncRNA; receptor; genome-wide association study; migration; translation; precision imaging; Capicua; TILs
• ISSN: 0022-3417; 1096-9896; 1096-9896
• DOI: 10.1002/path.5425

This year's Annual Review Issue of The Journal of Pathology contains 18 invited reviews on current research areas in pathology. The subject areas reflect the broad range of topics covered by the journal and this year encompass the development and application of software in digital histopathology, implementation of biomarkers in pathology practice; genetics and epigenetics, and stromal influences in disease. The reviews are authored by experts in their field and provide comprehensive updates in the chosen areas, in which there has been considerable recent progress in our understanding of disease. © 2020 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.