Biocompatible Material‐Based Flexible Biosensors: From Materials Design to Wearable/Implantable Devices and Integrated Sensing Systems

Human beings have a greater need to pursue life and manage personal or family health in the context of the rapid growth of artificial intelligence, big data, the Internet of Things, and 5G/6G technologies. The application of micro biosensing devices is crucial in connecting technology and personaliz...

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Published inSmall (Weinheim an der Bergstrasse, Germany) Vol. 19; no. 27; pp. e2207879 - n/a
Main Authors Liu, Gang, Lv, Ziyu, Batool, Saima, Li, Ming‐Zheng, Zhao, Pengfei, Guo, Liangchao, Wang, Yan, Zhou, Ye, Han, Su‐Ting
Format Journal Article
LanguageEnglish
Published Germany Wiley Subscription Services, Inc 01.07.2023
Subjects
Artificial intelligence
Biocompatibility
biocompatible materials
Biomedical materials
Biosensors
Chemical sensors
flexible biosensors
Inorganic materials
Internet of Things
in‐sensor computing
Nanotechnology
Organic materials
Temperature sensors
transistors
Wearable technology
wearable/implantable devices
flexible biosensors
biocompatible materials
wearable/implantable devices
in-sensor computing
transistors
Online AccessGet full text
ISSN1613-6810
1613-6829
1613-6829
DOI10.1002/smll.202207879

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Abstract Human beings have a greater need to pursue life and manage personal or family health in the context of the rapid growth of artificial intelligence, big data, the Internet of Things, and 5G/6G technologies. The application of micro biosensing devices is crucial in connecting technology and personalized medicine. Here, the progress and current status from biocompatible inorganic materials to organic materials and composites are reviewed and the material‐to‐device processing is described. Next, the operating principles of pressure, chemical, optical, and temperature sensors are dissected and the application of these flexible biosensors in wearable/implantable devices is discussed. Different biosensing systems acting in vivo and in vitro, including signal communication and energy supply are then illustrated. The potential of in‐sensor computing for applications in sensing systems is also discussed. Finally, some essential needs for commercial translation are highlighted and future opportunities for flexible biosensors are considered. Flexible biosensors (pressure, optical, temperature, and electrochemical sensors) prepared from various biocompatible materials have the capability to monitor physiological signals such as heart rate, temperature, and body fluid markers. Sophisticated wearable/implantable sensors and systems for optimizing every aspect of the personal health and performance can be achieved through rational design of functional material and device architecture, as well as the use of advanced processing/integration approaches.
AbstractList Human beings have a greater need to pursue life and manage personal or family health in the context of the rapid growth of artificial intelligence, big data, the Internet of Things, and 5G/6G technologies. The application of micro biosensing devices is crucial in connecting technology and personalized medicine. Here, the progress and current status from biocompatible inorganic materials to organic materials and composites are reviewed and the material-to-device processing is described. Next, the operating principles of pressure, chemical, optical, and temperature sensors are dissected and the application of these flexible biosensors in wearable/implantable devices is discussed. Different biosensing systems acting in vivo and in vitro, including signal communication and energy supply are then illustrated. The potential of in-sensor computing for applications in sensing systems is also discussed. Finally, some essential needs for commercial translation are highlighted and future opportunities for flexible biosensors are considered.
Human beings have a greater need to pursue life and manage personal or family health in the context of the rapid growth of artificial intelligence, big data, the Internet of Things, and 5G/6G technologies. The application of micro biosensing devices is crucial in connecting technology and personalized medicine. Here, the progress and current status from biocompatible inorganic materials to organic materials and composites are reviewed and the material‐to‐device processing is described. Next, the operating principles of pressure, chemical, optical, and temperature sensors are dissected and the application of these flexible biosensors in wearable/implantable devices is discussed. Different biosensing systems acting in vivo and in vitro, including signal communication and energy supply are then illustrated. The potential of in‐sensor computing for applications in sensing systems is also discussed. Finally, some essential needs for commercial translation are highlighted and future opportunities for flexible biosensors are considered. Flexible biosensors (pressure, optical, temperature, and electrochemical sensors) prepared from various biocompatible materials have the capability to monitor physiological signals such as heart rate, temperature, and body fluid markers. Sophisticated wearable/implantable sensors and systems for optimizing every aspect of the personal health and performance can be achieved through rational design of functional material and device architecture, as well as the use of advanced processing/integration approaches.
Human beings have a greater need to pursue life and manage personal or family health in the context of the rapid growth of artificial intelligence, big data, the Internet of Things, and 5G/6G technologies. The application of micro biosensing devices is crucial in connecting technology and personalized medicine. Here, the progress and current status from biocompatible inorganic materials to organic materials and composites are reviewed and the material-to-device processing is described. Next, the operating principles of pressure, chemical, optical, and temperature sensors are dissected and the application of these flexible biosensors in wearable/implantable devices is discussed. Different biosensing systems acting in vivo and in vitro, including signal communication and energy supply are then illustrated. The potential of in-sensor computing for applications in sensing systems is also discussed. Finally, some essential needs for commercial translation are highlighted and future opportunities for flexible biosensors are considered.Human beings have a greater need to pursue life and manage personal or family health in the context of the rapid growth of artificial intelligence, big data, the Internet of Things, and 5G/6G technologies. The application of micro biosensing devices is crucial in connecting technology and personalized medicine. Here, the progress and current status from biocompatible inorganic materials to organic materials and composites are reviewed and the material-to-device processing is described. Next, the operating principles of pressure, chemical, optical, and temperature sensors are dissected and the application of these flexible biosensors in wearable/implantable devices is discussed. Different biosensing systems acting in vivo and in vitro, including signal communication and energy supply are then illustrated. The potential of in-sensor computing for applications in sensing systems is also discussed. Finally, some essential needs for commercial translation are highlighted and future opportunities for flexible biosensors are considered.
Author Liu, Gang
Li, Ming‐Zheng
Lv, Ziyu
Zhao, Pengfei
Zhou, Ye
Han, Su‐Ting
Guo, Liangchao
Batool, Saima
Wang, Yan
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  surname: Liu
  fullname: Liu, Gang
  organization: Shenzhen University
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  givenname: Ziyu
  surname: Lv
  fullname: Lv, Ziyu
  email: lvziyu@szu.edu.cn
  organization: Shenzhen University
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  givenname: Saima
  surname: Batool
  fullname: Batool, Saima
  organization: Shenzhen University
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  givenname: Ming‐Zheng
  surname: Li
  fullname: Li, Ming‐Zheng
  organization: MGI Tech Co., Ltd
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  givenname: Pengfei
  surname: Zhao
  fullname: Zhao, Pengfei
  organization: Shenzhen University
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  givenname: Liangchao
  surname: Guo
  fullname: Guo, Liangchao
  organization: Yangzhou University
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  surname: Wang
  fullname: Wang, Yan
  organization: Hefei University of Technology
– sequence: 8
  givenname: Ye
  surname: Zhou
  fullname: Zhou, Ye
  organization: Shenzhen University
– sequence: 9
  givenname: Su‐Ting
  orcidid: 0000-0003-3392-7569
  surname: Han
  fullname: Han, Su‐Ting
  email: sutinghan@szu.edu.cn
  organization: Shenzhen University
BackLink https://www.ncbi.nlm.nih.gov/pubmed/37009995$$D View this record in MEDLINE/PubMed
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Snippet Human beings have a greater need to pursue life and manage personal or family health in the context of the rapid growth of artificial intelligence, big data,...
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SubjectTerms Artificial intelligence
Biocompatibility
biocompatible materials
Biomedical materials
Biosensors
Chemical sensors
flexible biosensors
Inorganic materials
Internet of Things
in‐sensor computing
Nanotechnology
Organic materials
Temperature sensors
transistors
Wearable technology
wearable/implantable devices
Title Biocompatible Material‐Based Flexible Biosensors: From Materials Design to Wearable/Implantable Devices and Integrated Sensing Systems
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https://www.ncbi.nlm.nih.gov/pubmed/37009995
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Volume 19
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