Fractal Structure of Brain Electrical Activity of Patients With Mental Disorders

• Published in: Frontiers in physiology Vol. 13; p. 905318
• Main Authors: E, Dick O., V, Murav’eva S., S, Lebedev V., E, Shelepin Yu
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 13.07.2022
• Subjects: brain activity; depression; multifractality; Physiology; schizophrenia; singularity spectrum
• ISSN: 1664-042X; 1664-042X
• DOI: 10.3389/fphys.2022.905318

This work was aimed at a comparative analysis of the degree of multifractality of electroencephalographic time series obtained from a group of healthy subjects and from patients with mental disorders. We analyzed long-term records of patients with paranoid schizophrenia and patients with depression. To evaluate the properties of multifractal scaling of various electroencephalographic time series, the method of maximum modulus of the wavelet transform and multifractal analysis of fluctuations without a trend were used. The stability of the width and position of the singularity spectrum for each of the test groups was revealed, and a relationship was established between the correlation and anticorrelation dynamics of successive values of the electroencephalographic time series and the type of mental disorders. It was shown that the main differences between the multifractal properties of brain activity in normal and pathological conditions lie in the different width of the multifractality spectrum and its location associated with the correlated or anticorrelated dynamics of the values of successive time series. It was found that the schizophrenia group is characterized by a greater degree of multifractality compared to the depression group. Thus, the degree of multifractality can be included in a set of tests for differential diagnosis and research of mental disorders.