Hepatocellular carcinoma in a chronic hepatitis C patient 15 years after achieving a sustained virological response

An 84-year-old female with chronic hepatitis C (HCV) was treated with interferon (IFN) and achieved sustained virological response (SVR) 15 years ago. She was then followed-up by blood tests with tumor markers and ultrasound (US) examinations every 6 months. Fifteen years later, a hepatocellular car...

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Published inKanzo Vol. 53; no. 11; pp. 763 - 768
Main Authors Watanabe, Emiri, Takada, Yasutsugu, Hiasa, Yoichi, Hirooka, Masashi, Tada, Fujimasa, Tokumoto, Yoshio, Tohyama, Taiji, Koizumi, Yohei, Onji, Morikazu, Ochi, Hironori, Abe, Masanori, Yonenaga, Yoshikuni, Ishihara, Toru
Format Journal Article
LanguageEnglish
Japanese
Published The Japan Society of Hepatology 2012
Subjects
hepatitis C
hepatocellular carcinoma
interferon
long term
sustained virological response
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ISSN0451-4203
1881-3593
1881-3593
DOI10.2957/kanzo.53.763

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Summary:An 84-year-old female with chronic hepatitis C (HCV) was treated with interferon (IFN) and achieved sustained virological response (SVR) 15 years ago. She was then followed-up by blood tests with tumor markers and ultrasound (US) examinations every 6 months. Fifteen years later, a hepatocellular carcinoma (HCC) tumor was detected as a 21-mm-diameter nodule. Hepatic resection was performed, and the pathological diagnosis was moderately differentiated HCC, trabecular type. Regular, long-term follow-up that includes screening with blood tests and imaging is needed for patients with HCV, even those who achieve SVR after IFN treatment.
ISSN:0451-4203
1881-3593
1881-3593
DOI:10.2957/kanzo.53.763