Metabolomic diagnostics and human digital image

• Published in: Personalized medicine Vol. 16; no. 2; pp. 133 - 144
• Main Authors: Balashova, Elena E, Lokhov, Petr G, Ponomarenko, Elena A, Markin, Sergey S, Lisitsa, Andrey V, Archakov, Alexander I
• Format: Journal Article
• Language: English
• Published: England Future Medicine Ltd 01.03.2019
• Subjects: Analytical chemistry; Antigens; Biomarkers; blood; Chromatography; Data processing; Diabetes; Diagnosis; direct mass spectrometry; Disease; Genomes; Genomics; human digital image; Laboratories; laboratory-based diagnostics; Lung cancer; Mass spectrometry; Medical screening; Medicine; Metabolism; Metabolites; Metabolomics; NMR; Nuclear magnetic resonance; Nutrition research; Ovarian cancer; Patients; precision medicine; Prostate cancer; Proteomics; Scientific imaging; precision medicine; direct mass spectrometry; laboratory-based diagnostics; metabolomics; blood; human digital image
• ISSN: 1741-0541; 1744-828X; 1744-828X
• DOI: 10.2217/pme-2018-0066

The existing clinical laboratory practice has limitations in terms of specificity and sensitivity of diagnosis, making the introduction of new methods in medicine more topical. Application of 'omics' technologies, especially metabolomics, allows overcoming these limitations. The composition of blood metabolites reflects the physical state of an organism at the molecular level. The analysis of blood metabolome can serve as effective means of diagnosis, implementation of which in healthcare is timely and relevant. This paper demonstrates the versatility of metabolomic diagnostics, its applicability to various diseases. We discussed the standard of human digital image, which includes the metabolomic data sufficient to make an accurate assessment of general health and carry out precision diagnostics of a wide range of diseases.