Potential of Renal Pathology on Refining Syndrome Typing of Chinese Medicine in IgA Nephropathy

Objective： To investigate the potential of renal pathological index as a differential diagnosis factor for Chinese medicine （CM） syndromes typing in IgA nephropathy （IgAN）. Methods： A total of 1,016 patients with IgAN was recruited from November 2001 to November 2004. All the signs and symptoms incl...

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Bibliographic Details
Published inChinese journal of integrative medicine Vol. 19; no. 2; pp. 92 - 97
Main Author 李建军 陈香美 魏日胞
Format Journal Article
LanguageEnglish
Published Heidelberg Chinese Association of Traditional and Western Medicine 01.02.2013
Subjects
Adolescent
Adult
Aged
Child
Child, Preschool
Female
Glomerulonephritis, IGA - classification
Glomerulonephritis, IGA - immunology
Glomerulonephritis, IGA - pathology
Glomerulonephritis, IGA - therapy
Humans
IgA肾病
Kidney - blood supply
Kidney - pathology
Kidney Glomerulus - pathology
Male
Medicine
Medicine & Public Health
Medicine, Chinese Traditional
Middle Aged
Original Article
Renal Artery - pathology
Syndrome
Young Adult
中国医药
病理
精炼
肾小球
肾脏
证型
鉴别诊断
Chinese medicine
IgA nephropathy
pattern diagnosis
renal pathology
syndrome differentiation
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ISSN1672-0415
1993-0402
1993-0402
DOI10.1007/s11655-012-1214-8

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Summary:Objective： To investigate the potential of renal pathological index as a differential diagnosis factor for Chinese medicine （CM） syndromes typing in IgA nephropathy （IgAN）. Methods： A total of 1,016 patients with IgAN was recruited from November 2001 to November 2004. All the signs and symptoms including picture of the tongue and pulse tracings were collected. All patients were typed according to the CM syndrome typing scheme for chronic primary glomerulopathy. The severity of glomerulus and tubulointerstitial lesions （mild, moderate- severe） were evaluated using lee＇s grading system and the Katafuchi score system. Results： The syndrome types transform in turn by deficiency of both the Spleen （Pi） and Lung （Fei） qi, deficiency of both qi and yin, deficiency of Liver （Gan） and Kidney （Shen） yin and deficiency of Spleen-Kidney （Shen） yang, with the aggravation of pathogenetic condition and that the manifestation of deficiency of qi clinically showed proliferative lesion of glomerular mesangium, while the glomerular sclerosis pathologically showed the manifestation of yin deficiency. Conclusion： Renal pathological findings may be a candidate of objective factors to refine CM syndrome typing process.
Bibliography:IgA nephropathy, Chinese medicine, renal pathology, syndrome differentiation, pattern diagnosis
11-4928/R
Objective： To investigate the potential of renal pathological index as a differential diagnosis factor for Chinese medicine （CM） syndromes typing in IgA nephropathy （IgAN）. Methods： A total of 1,016 patients with IgAN was recruited from November 2001 to November 2004. All the signs and symptoms including picture of the tongue and pulse tracings were collected. All patients were typed according to the CM syndrome typing scheme for chronic primary glomerulopathy. The severity of glomerulus and tubulointerstitial lesions （mild, moderate- severe） were evaluated using lee＇s grading system and the Katafuchi score system. Results： The syndrome types transform in turn by deficiency of both the Spleen （Pi） and Lung （Fei） qi, deficiency of both qi and yin, deficiency of Liver （Gan） and Kidney （Shen） yin and deficiency of Spleen-Kidney （Shen） yang, with the aggravation of pathogenetic condition and that the manifestation of deficiency of qi clinically showed proliferative lesion of glomerular mesangium, while the glomerular sclerosis pathologically showed the manifestation of yin deficiency. Conclusion： Renal pathological findings may be a candidate of objective factors to refine CM syndrome typing process.
LI Jian-jun , CHEN Xiang-mei , WEI Ri-bao
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1672-0415
1993-0402
1993-0402
DOI:10.1007/s11655-012-1214-8