Receptors for secretin, calcitonin, parathyroid hormone (PTH)/PTH-related peptide, vasoactive intestinal peptide, glucagonlike peptide 1, growth hormone-releasing hormone, and glucagon belong to a newly discovered G-protein-linked receptor family

Seven receptors with highly homologous structural features have recently been discovered that belong to a new family of seven membrane-spanning receptors within the G-protein-linked receptor superfamily. These seven all bind small peptide ligands, and many have the unique property to activate the G...

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Bibliographic Details
Published inTrends in endocrinology and metabolism Vol. 4; no. 10; pp. 309 - 314
Main Authors Segre, Gino V., Goldring, Steven R.
Format Journal Article
LanguageEnglish
Published London Elsevier Ltd 01.12.1993
Elsevier
Subjects
Biological and medical sciences
Cell receptors
Cell structures and functions
Fundamental and applied biological sciences. Psychology
Hormone receptors. Growth factor receptors. Cytokine receptors. Prostaglandin receptors
Molecular and cellular biology
Glucagon
Peptide hormone
Secretin
Review
Glucagon like peptide 1
Parathormone
Membrane receptor
Calcitonin
Parathyroid hormone related peptide
VIP
G protein
Hormonal receptor
STH-RH
Online AccessGet full text
ISSN1043-2760
1879-3061
DOI10.1016/1043-2760(93)90071-L

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Summary:Seven receptors with highly homologous structural features have recently been discovered that belong to a new family of seven membrane-spanning receptors within the G-protein-linked receptor superfamily. These seven all bind small peptide ligands, and many have the unique property to activate the G S and at least one other G protein.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1043-2760
1879-3061
DOI:10.1016/1043-2760(93)90071-L