Acute Uveitis following COVID-19 Vaccination

• Published in: Ocular immunology and inflammation Vol. 29; no. 6; pp. 1207 - 1209
• Main Authors: ElSheikh, Reem H., Haseeb, Abid, Eleiwa, Taher K., Elhusseiny, Abdelrahman M.
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 18.08.2021
• Subjects: Acute Disease; Administration, Ophthalmic; Adolescent; COVID-19 - prevention & control; COVID-19 Vaccines - adverse effects; Female; Glucocorticoids - administration & dosage; Humans; Ophthalmic Solutions; Retrospective Studies; SARS-CoV-2; Tomography, Optical Coherence; Uveitis, Anterior - diagnosis; Uveitis, Anterior - drug therapy; Uveitis, Anterior - etiology; Vaccination - adverse effects; Visual Acuity - physiology
• ISSN: 0927-3948; 1744-5078; 1744-5078
• DOI: 10.1080/09273948.2021.1962917

To describe a case of juvenile idiopathic arthritis (JIA)-associated anterior uveitis after receiving the Sinopharm COVID-19 vaccine. A retrospective case report. An 18-year-old girl, with a history of antinuclear antibody positive oligoarticular JIA, presented with bilateral anterior uveitis 5 days after the second dose of the Sinopharm COVID-19 vaccine. Ocular examination revealed anterior uveitis with reduced visual acuity in both eyes. Anterior segment optical coherence tomography showed hyperreflective dots in the anterior chamber (AC) and fine endothelial granularities representing the circulating cells in the AC. Uveitis in both eyes resolved gradually after topical steroid treatment without recurrence. This report demonstrates a potential causal association of COVID-19 vaccine with anterior uveitis.