Bio-interfacial magnetic resonance imaging of hyperpolarized contrast agents for metabolic flux interrogation in vivo

We utilized dynamic nuclear polarization to hyperpolarize three metabolic imaging agents as single agents and together (co-polarization with two different organic radicals; OX63 and BDPA). In addition, we describe our initial two slice selective spectroscopy in vivo experiments in mice. These techni...

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Published inJournal of industrial and engineering chemistry (Seoul, Korea) Vol. 36; pp. 224 - 228
Main Authors Jeong, Gijin, Lee, Jee-Wook, Gong, Gyeonghyeon, Ko, Hyeji, Choi, Ikjang, Seo, Hyeonglim, Lee, Youngbok, Millward, Niki M. Zacharias, Bhattacharya, Pratip K.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 25.04.2016
한국공업화학회
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ISSN1226-086X
1876-794X
DOI10.1016/j.jiec.2016.02.002

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Abstract We utilized dynamic nuclear polarization to hyperpolarize three metabolic imaging agents as single agents and together (co-polarization with two different organic radicals; OX63 and BDPA). In addition, we describe our initial two slice selective spectroscopy in vivo experiments in mice. These techniques along with advances by other laboratories will allow for multiple metabolic pathways to be imaged in real-time and in vivo.
AbstractList We utilized dynamic nuclear polarization to hyperpolarize three metabolic imaging agents as single agents and together (co-polarization with two different organic radicals; OX63 and BDPA). In addition, we describe our initial two slice selective spectroscopy in vivo experiments in mice. These techniques along with advances by other laboratories will allow for multiple metabolic pathways to be imaged in real-time and in vivo.
We utilized dynamic nuclear polarization to hyperpolarize three metabolic imaging agents as singleagents and together (co-polarization with two different organic radicals; OX63 and BDPA). In addition,we describe our initial two slice selective spectroscopy in vivo experiments in mice. These techniquesalong with advances by other laboratories will allow for multiple metabolic pathways to be imaged inreal-time and in vivo. KCI Citation Count: 1
Author Ko, Hyeji
Millward, Niki M. Zacharias
Seo, Hyeonglim
Lee, Youngbok
Bhattacharya, Pratip K.
Choi, Ikjang
Jeong, Gijin
Lee, Jee-Wook
Gong, Gyeonghyeon
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  fullname: Bhattacharya, Pratip K.
  organization: Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, United States
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10.1038/nature07017
10.1039/C4CC06199C
10.1038/nm1650
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10.1002/jmri.10172
10.1158/0008-5472.CAN-06-2564
10.1021/jp302399f
10.1073/pnas.1733835100
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Keywords Dynamic nuclear polarization
In vivo metabolic MR
MR spectroscopy and imaging
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References Warburg (bib0085) 1956; 123
Golman, in’t Zandt, Lerche, Pehrson, Ardenkjaer-Larsen (bib0115) 2006; 66
Gallagher, Kettunen, Day, Hu, Ardenkjaer-Larsen, Zandt, Jensen, Karlsson, Golman, Lerche, Brindle (bib0150) 2008; 453
Zacharias, Chan, Sailasuta, Ross, Bhattacharya (bib0155) 2011; 134
Kurhanewicz, Swanson, Nelson, Vigneron (bib0090) 2002; 16
Lee (bib0110) 2016; 51
Lee, Zacharias, Piwnica-Worms, Bhattacharya (bib0145) 2014; 50
Ardenkjaer-Larsen, Fridlund, Gram, Hansson, Hansson, Lerche, Servin, Thaning, Golman (bib0105) 2003; 100
Wilson, Kurhanewicz (bib0140) 2014; 55
Golman, Ardenaer-Larsen, Petersson, Mansson, Leunbach (bib0125) 2003; 100
Lumata, Merritt, Malloy, Sherry, Kovacs (bib0160) 2012; 116
Nelson, Kurhanewicz, Vigneron, Larson, Harzstark, Ferrone, van Criekinge, Chang, Bok, Park, Reed, Carvajal, Small, Munster, Weinberg, Ardenkjaer-Larsen, Chen, Hurd, Odegardstuen, Robb, Tropp, Murray (bib0135) 2013; 5
Spratlin, Serkova, Eckhardt (bib0095) 2009; 15
Abragam, Goldman (bib0100) 1978; 41
Keshari, Wilson (bib0120) 2014; 43
Day, Kettunen, Gallagher, Hu, Lerche, Wolber, Golman, Ardenkjaer-Larsen, Brindle (bib0130) 2007; 13
Kurhanewicz (10.1016/j.jiec.2016.02.002_bib0090) 2002; 16
Lumata (10.1016/j.jiec.2016.02.002_bib0160) 2012; 116
Golman (10.1016/j.jiec.2016.02.002_bib0115) 2006; 66
Warburg (10.1016/j.jiec.2016.02.002_bib0085) 1956; 123
Gallagher (10.1016/j.jiec.2016.02.002_bib0150) 2008; 453
Lee (10.1016/j.jiec.2016.02.002_bib0110) 2016; 51
Keshari (10.1016/j.jiec.2016.02.002_bib0120) 2014; 43
Nelson (10.1016/j.jiec.2016.02.002_bib0135) 2013; 5
Wilson (10.1016/j.jiec.2016.02.002_bib0140) 2014; 55
Ardenkjaer-Larsen (10.1016/j.jiec.2016.02.002_bib0105) 2003; 100
Day (10.1016/j.jiec.2016.02.002_bib0130) 2007; 13
Spratlin (10.1016/j.jiec.2016.02.002_bib0095) 2009; 15
Golman (10.1016/j.jiec.2016.02.002_bib0125) 2003; 100
Lee (10.1016/j.jiec.2016.02.002_bib0145) 2014; 50
Zacharias (10.1016/j.jiec.2016.02.002_bib0155) 2011; 134
Abragam (10.1016/j.jiec.2016.02.002_bib0100) 1978; 41
References_xml – volume: 16
  start-page: 451
  year: 2002
  ident: bib0090
  publication-title: J. Magn. Reson. Imaging
– volume: 50
  start-page: 13030
  year: 2014
  ident: bib0145
  publication-title: Chem. Commun.
– volume: 66
  start-page: 10855
  year: 2006
  ident: bib0115
  publication-title: Cancer Res.
– volume: 116
  start-page: 5129
  year: 2012
  ident: bib0160
  publication-title: J. Phys. Chem. A
– volume: 134
  start-page: 934
  year: 2011
  ident: bib0155
  publication-title: J. Am. Chem. Soc.
– volume: 41
  start-page: 395
  year: 1978
  ident: bib0100
  publication-title: Rep. Prog. Phys.
– volume: 453
  start-page: 940
  year: 2008
  ident: bib0150
  publication-title: Nature
– volume: 123
  start-page: 309
  year: 1956
  ident: bib0085
  publication-title: Science
– volume: 51
  start-page: 190
  year: 2016
  ident: bib0110
  publication-title: Appl. Spectrosc. Rev.
– volume: 13
  start-page: 1382
  year: 2007
  ident: bib0130
  publication-title: Nat. Med.
– volume: 5
  start-page: 198ra108
  year: 2013
  ident: bib0135
  publication-title: Sci. Transl. Med.
– volume: 55
  start-page: 1567
  year: 2014
  ident: bib0140
  publication-title: J. Nucl. Med.
– volume: 100
  start-page: 10158
  year: 2003
  ident: bib0105
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
– volume: 15
  start-page: 431
  year: 2009
  ident: bib0095
  publication-title: Clin. Cancer Res.
– volume: 43
  start-page: 1627
  year: 2014
  ident: bib0120
  publication-title: Chem. Soc. Rev.
– volume: 100
  start-page: 10435
  year: 2003
  ident: bib0125
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
– volume: 43
  start-page: 1627
  year: 2014
  ident: 10.1016/j.jiec.2016.02.002_bib0120
  publication-title: Chem. Soc. Rev.
  doi: 10.1039/C3CS60124B
– volume: 15
  start-page: 431
  year: 2009
  ident: 10.1016/j.jiec.2016.02.002_bib0095
  publication-title: Clin. Cancer Res.
  doi: 10.1158/1078-0432.CCR-08-1059
– volume: 41
  start-page: 395
  year: 1978
  ident: 10.1016/j.jiec.2016.02.002_bib0100
  publication-title: Rep. Prog. Phys.
  doi: 10.1088/0034-4885/41/3/002
– volume: 453
  start-page: 940
  year: 2008
  ident: 10.1016/j.jiec.2016.02.002_bib0150
  publication-title: Nature
  doi: 10.1038/nature07017
– volume: 50
  start-page: 13030
  year: 2014
  ident: 10.1016/j.jiec.2016.02.002_bib0145
  publication-title: Chem. Commun.
  doi: 10.1039/C4CC06199C
– volume: 13
  start-page: 1382
  year: 2007
  ident: 10.1016/j.jiec.2016.02.002_bib0130
  publication-title: Nat. Med.
  doi: 10.1038/nm1650
– volume: 5
  start-page: 198ra108
  year: 2013
  ident: 10.1016/j.jiec.2016.02.002_bib0135
  publication-title: Sci. Transl. Med.
  doi: 10.1126/scitranslmed.3006070
– volume: 16
  start-page: 451
  year: 2002
  ident: 10.1016/j.jiec.2016.02.002_bib0090
  publication-title: J. Magn. Reson. Imaging
  doi: 10.1002/jmri.10172
– volume: 66
  start-page: 10855
  year: 2006
  ident: 10.1016/j.jiec.2016.02.002_bib0115
  publication-title: Cancer Res.
  doi: 10.1158/0008-5472.CAN-06-2564
– volume: 116
  start-page: 5129
  year: 2012
  ident: 10.1016/j.jiec.2016.02.002_bib0160
  publication-title: J. Phys. Chem. A
  doi: 10.1021/jp302399f
– volume: 100
  start-page: 10158
  year: 2003
  ident: 10.1016/j.jiec.2016.02.002_bib0105
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1733835100
– volume: 51
  start-page: 190
  year: 2016
  ident: 10.1016/j.jiec.2016.02.002_bib0110
  publication-title: Appl. Spectrosc. Rev.
– volume: 100
  start-page: 10435
  year: 2003
  ident: 10.1016/j.jiec.2016.02.002_bib0125
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.1733836100
– volume: 134
  start-page: 934
  year: 2011
  ident: 10.1016/j.jiec.2016.02.002_bib0155
  publication-title: J. Am. Chem. Soc.
  doi: 10.1021/ja2040865
– volume: 123
  start-page: 309
  year: 1956
  ident: 10.1016/j.jiec.2016.02.002_bib0085
  publication-title: Science
  doi: 10.1126/science.123.3191.309
– volume: 55
  start-page: 1567
  year: 2014
  ident: 10.1016/j.jiec.2016.02.002_bib0140
  publication-title: J. Nucl. Med.
  doi: 10.2967/jnumed.114.141705
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Snippet We utilized dynamic nuclear polarization to hyperpolarize three metabolic imaging agents as single agents and together (co-polarization with two different...
We utilized dynamic nuclear polarization to hyperpolarize three metabolic imaging agents as singleagents and together (co-polarization with two different...
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SubjectTerms Contrast agents
Dynamic nuclear polarization
Flux
Hyperpolarization
In vivo metabolic MR
In vivo methods and tests
Interrogation
MR spectroscopy and imaging
Polarization
Radicals
Real time
Spectroscopy
화학공학
Title Bio-interfacial magnetic resonance imaging of hyperpolarized contrast agents for metabolic flux interrogation in vivo
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