Metal–organic frameworks (MOFs) based chemosensors/biosensors for analysis of food contaminants

• Published in: Trends in food science & technology Vol. 118; pp. 569 - 588
• Main Authors: Zhang, Zhihong, Lou, Yafei, Guo, Chuanpan, Jia, Qiaojuan, Song, Yingpan, Tian, Jia-Yue, Zhang, Shuai, Wang, Minghua, He, Linghao, Du, Miao
• Format: Journal Article
• Language: English
• Published: Cambridge Elsevier Ltd 01.12.2021; Elsevier BV
• Subjects: Analysis of food contaminants; Analytical chemistry; Antibiotics; Antibodies; Aptamers; Biosensors; Chemical sensors; chemical species; Chemoreceptors; Chemosensors; Contaminants; DNA; DNA probes; Economic impact; Electrochemistry; Electrode materials; electrodes; Emitters; Fluorescence; Food additives; Food analysis; Food contamination; Food industry; Food safety; Hazardous materials; Heavy metals; human health; Metal ions; Metal-organic frameworks; Metal–organic frameworks (MOFs); oligonucleotides; Platforms; Porosity; Porous materials; Raman spectroscopy; Reliability analysis; Safety; technology; Metal–organic frameworks (MOFs); Food safety; Biosensors; Analysis of food contaminants; Chemosensors
• ISSN: 0924-2244; 1879-3053
• DOI: 10.1016/j.tifs.2021.10.024

As a critical topic of international concern, food safety has received great attention in recent years. The hazardous substances (such as antibiotics, heavy metal ions, food additives, and foodborne bacteria) in foodstuffs would cause threat to human health and economic losses in food industry. Despite of high sensitivity, accuracy, and reliability of conventional techniques for analysis of food contaminants, they often require complicated apparatus, well-trained personalized operation, and laborious and time-consuming procedure. In this regard, new sensing strategies for convenient, fast, and sensitive detection of food contaminants should be developed for food safety. Metal–organic frameworks (MOFs), as a large category of porous crystalline materials, could be used as efficient platforms for constructing diverse chemosensors and biosensors, for their high porosity, adjustable compositions or structures, and good stability. A variety of MOFs, MOFs-based composites, and MOFs-based derivatives show excellent fluorescence (FL), chemical functionality, and strong bioaffinity toward probes (DNA, aptamers, or antibodies), exhibiting great potentials as FL emitters, electrode materials, or platforms of biosensors for selective and sensitive detection of hazard analytes in foodstuffs. By coupling with different determination techniques such as FL, electrochemical (EC), photoelectrochemical (PEC) or surface-enhanced Raman spectroscopy methods, MOFs-based materials have shown promising applications for detecting diverse analytes. Furthermore, the current challenges and future developments of MOFs-based materials for analysis of food contaminants have been discussed. Although some reviews on the applications of MOFs in food packing and food safety have been documented, this comprehensive review will provide new insights to the construction of chemosensors and biosensors with MOFs-based materials for determination of food contaminants toward food safety monitoring. [Display omitted] •A comprehensive review on MOFs-based chemosensors/biosensors for food safety.•Discussion on the determination platforms and techniques for food contaminants.•Development of MOFs-based chemosensors/biosensors for various food contaminants.