Platelet rich fibrin in treatment of penile skin defects. A case series and review of the literature

Treatment of complex and chronic wounds often remains a challenge for clinicians, carrying a severe impact on the wellbeing of patients and the health care system. Leukocyte-and Platelet rich fibrin (L-PRF) is an autologous platelet product with regenerative properties that can be used to stimulate...

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Bibliographic Details
Published inUrology case reports Vol. 63; p. 103198
Main Authors Lamers, Glenn, Royakkers, Laurence, Schapmans, Stijn, De Coster, Katrien, Zabegalina, Natalia, Van Dyck, Johan
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.11.2025
Subjects
Platelet rich fibrin
Reconstructive urology
Regeneration
Urologic surgery
Regeneration
Platelet rich fibrin
Reconstructive urology
Urologic surgery
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ISSN2214-4420
2214-4420
DOI10.1016/j.eucr.2025.103198

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Summary:Treatment of complex and chronic wounds often remains a challenge for clinicians, carrying a severe impact on the wellbeing of patients and the health care system. Leukocyte-and Platelet rich fibrin (L-PRF) is an autologous platelet product with regenerative properties that can be used to stimulate and accelerate wound healing. Its usage in oral surgery and dentistry is well established but evidence in urologic surgery is limited. We report two cases with extensive penile cutaneous defects after surgical debridement, treated with L-PRF technology and review the available literature regarding its utilization in the field of urology.
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ISSN:2214-4420
2214-4420
DOI:10.1016/j.eucr.2025.103198