Wells' syndrome associated with ulcerative colitis: a case report and literature review

Wells' syndrome, also termed eosinophilic cellulitis, is a dermatologic condition of unknown etiology that occurs as recurrent patches or plaques mimicking infectious cellulitis. Histopathology reveals an eosinophilic infiltrate and characteristic flame figures. Previous reports have associated...

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Bibliographic Details
Published inJournal of gastroenterology Vol. 42; no. 3; pp. 250 - 252
Main Authors Sakaria, Sonali S., Ravi, Anupama, Swerlick, Robert, Sitaraman, Shanthi
Format Journal Article
LanguageEnglish
Published Japan Springer Nature B.V 01.03.2007
Subjects
Adult
Cellulitis - epidemiology
Colitis, Ulcerative - epidemiology
Colonoscopy
Comorbidity
Eosinophilia - epidemiology
Female
Humans
Syndrome
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ISSN0944-1174
1435-5922
DOI10.1007/s00535-006-1985-9

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Summary:Wells' syndrome, also termed eosinophilic cellulitis, is a dermatologic condition of unknown etiology that occurs as recurrent patches or plaques mimicking infectious cellulitis. Histopathology reveals an eosinophilic infiltrate and characteristic flame figures. Previous reports have associated this syndrome with parasitic infections, arthropod bites, pharmacologic agents, surgery, and hematologic disorders. We present a case report of a patient with Wells' syndrome associated with newly diagnosed ulcerative colitis. The dermatosis erupted concurrently with flares of ulcerative colitis. Furthermore, treatment of the ulcerative colitis led to resolution of the skin lesions. To our knowledge this describes the first association between inflammatory bowel disease and Wells' syndrome and argues for a distinct relationship between the two.
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ISSN:0944-1174
1435-5922
DOI:10.1007/s00535-006-1985-9