Adenosine myocardial perfusion single photon emission computed tomographic stress testing 24–72 h after uncomplicated myocardial infarction

• Published in: The International Journal of Cardiovascular Imaging Vol. 18; no. 4; pp. 269 - 272
• Main Authors: Kulhanek, Jan, Sorrell, Vincent L., Ershadi, Reza E., Cabarrus, Brian R., Short, Douglas B., Movahed, Assad
• Format: Journal Article
• Language: English
• Published: Dordrecht Kluwer Academic Publishers 01.08.2002; Springer Nature B.V
• Subjects: Adenosine; Aged; Biological and medical sciences; Cardiology. Vascular system; Coronary heart disease; Exercise Test; Female; Heart; Humans; Male; Medical sciences; Myocardial Infarction - diagnostic imaging; Retrospective Studies; Safety; Time Factors; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents; Human; Adenosine; Purine nucleoside; Radiodiagnosis; Emission; Cardiovascular disease; Single photon emission tomography; Coronary heart disease; Myocardial disease; Photon; Stress; Perfusion; Medical imagery
• ISSN: 1569-5794; 1573-0743
• DOI: 10.1023/A:1015525311510

Safety of performing adenosine myocardial perfusion stress testing as early as 24 h after acute uncomplicated myocardial infarction is not known. We evaluated 31(14 females and 17 males, average age 72, range 46-89 years) consecutive patients with uncomplicated myocardial infarction, who underwent adenosine myocardial perfusion stress imaging, 24-72 h after infarction for risk stratification. Adenosine was infused at a rate of 140 microg/kg/min for 6 min. Twenty patients were presented with non-ST-elevation myocardial infarction. Eleven patients were admitted with acute ST-elevation myocardial infarction. Patients were monitored for signs of complication during and immediately after the stress test. The average time from admission to performance of stress tests was 51 +/- 19 h, ranging from the minimum of 24 h to maximum 72 h. No complications related to adenosine infusion were detected. In conclusion, our data suggest that a further large study of early adenosine myocardial perfusion SPECT imaging may be safe in a carefully selected group of patients after uncomplicated myocardial infarction.