Hemodynamic Modeling, Medical Imaging, and Machine Learning and Their Applications to Cardiovascular Interventions

• Published in: IEEE reviews in biomedical engineering Vol. 16; pp. 403 - 423
• Main Authors: Kadem, Mason, Garber, Louis, Abdelkhalek, Mohamed, Al-Khazraji, Baraa K., Keshavarz-Motamed, Zahra
• Format: Journal Article
• Language: English
• Published: United States IEEE 2023; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Anomalies; Cardiovascular disease; Cardiovascular Diseases; cardiovascular imaging; Computational modeling; Coronary artery disease; Data models; Decision making; Diagnostic Imaging; Economic impact; Economic models; Global health; Health services; Heart; Heart Diseases; hemodynamic modeling; Hemodynamics; Humans; Impact analysis; interventions; Learning algorithms; Machine Learning; Medical imaging; Modelling; Patients; Predictive models; Public health; Radiography; Solid modeling
• ISSN: 1937-3333; 1941-1189; 1941-1189
• DOI: 10.1109/RBME.2022.3142058

Cardiovascular disease is a deadly global health crisis that carries a substantial financial burden. Innovative treatment and management of cardiovascular disease straddles medicine, personalized hemodynamic modeling, machine learning, and modern imaging to help improve patient outcomes and reduce the economic impact. Hemodynamic modeling offers a non-invasive method to provide clinicians with new pre- and post- procedural metrics and aid in the selection of treatment options. Medical imaging is an integral part in clinical workflows for understanding and managing cardiac disease and interventions. Coupling machine learning with modeling, and cardiovascular imaging, provides faster modeling, improved data fidelity, and an enhanced understanding and earlier detection of cardiovascular anomalies, leading to the development of patient-specific diagnostic and predictive tools for characterizing and assessing cardiovascular outcomes. Herein, we provide a scoping review of translational hemodynamic modeling, medical imaging, and machine learning and their applications to cardiovascular interventions. We particularly focus on providing an intuitive understanding of each of these approaches and their ability to support decision making during important clinical milestones.