Diagnosing probable urinary tract infections in nursing home residents without indwelling catheters: a narrative review

• Published in: Clinical microbiology and infection Vol. 30; no. 12; pp. 1523 - 1528
• Main Authors: Llor, Carl, Moragas, Ana, Ruppe, Georg, Lykkegaard, Jesper, Hansen, Malene Plejdrup, Antsupova, Valeria S., Jensen, Jette Nygaard, Theut, Anna Marie, Petek, Davorina, Sodja, Nina, Kowalczyk, Anna, Bjerrum, Lars, Bjerrum, Anders, García-Sangenís, Ana, Modena, Daniela, Monfà, Ramon, Morros Pedrós, Rosa, Chalkidou, Athina, Marloth, Tina, Døssing Berntsen, Susanne, Døssing-Poulsen, Nina Camilla, Munck, Anders, Kanstrup Olsen, Jonas, Tang Hall, Asbjørn, López-Valcárcel, Beatriz González, Squaglia, Ana, Elistratova, Marina, Vallejo-Torres, Laura, Anastasaki, Marilena, Angelaki, Agapi, Karkana, Maria-Nefeli, Lionis, Christos, Petelos, Elena, Tsoulchai, Greta, Balint, András, Benkő, Ria, Álvarez, Laura, Briones, Sergi, Ricart, Marta, Godycki-Cwirko, Maciej, Glasa, Jozef, Glasová, Helena, Jaruseviciene, Lina, Radzeviciene, Ruta
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2024
• Subjects: Algorithms; Anti-Bacterial Agents - therapeutic use; Antibiotic prescribing; Bacteriuria; Bacteriuria - diagnosis; Catheters, Indwelling - adverse effects; Frail elderly; Humans; Nursing Homes; Prevalence; Signs and symptoms; Urinalysis; Urinary tract infection; Urinary Tract Infections - diagnosis; Nursing homes; Signs and symptoms; Urinary tract infection; Frail elderly; Bacteriuria; Urinalysis; Antibiotic prescribing
• ISSN: 1198-743X; 1469-0691; 1469-0691
• DOI: 10.1016/j.cmi.2024.08.020

Overdiagnosis of urinary tract infections (UTIs) is one of the most common reasons for the unnecessary use of antibiotics in nursing homes, increasing the risk of missing serious conditions. Various decision tools and algorithms aim to aid in UTI diagnosis and the initiation of antibiotic therapy for residents. However, due to the lack of a clear reference standard, these tools vary widely and can be complex, with some requiring urine testing. As part of the European-funded IMAGINE project, aimed at improving antibiotic use for UTIs in nursing home residents, we have reviewed the recommendations. This review provides a comprehensive summary of the more relevant tools and algorithms aimed at identifying true UTIs among residents living in nursing homes and discusses the challenges in using these algorithms based on updated research. The discussion is based on a relevant medical literature search and synthesis of the findings and published tools to provide an overview of the current state of improving the diagnosis of UTIs in nursing homes. The following topics are covered: prevalence of asymptomatic bacteriuria, diagnostic challenges, clinical criteria, urinary testing, and algorithms to be implemented in nursing home facilities. Diagnosing UTIs in residents is challenging due to the high prevalence of asymptomatic bacteriuria and nonspecific urinary tract signs and symptoms among those with suspected UTIs. The fear of missing a UTI and the perceived antibiotic demands from residents and relatives might lead to overdiagnosis of this common condition. Despite their widespread use, urine dipsticks should not be recommended for geriatric patients. Patients who do not meet the minimum diagnostic criteria for UTIs should be evaluated for alternative conditions. Adherence to a simple algorithm can prevent unnecessary antibiotic courses without compromising resident safety.