A Gas Chromatographic Stationary of Homochiral Metal-peptide Framework Material and Its Applications

• Published in: Chemical research in Chinese universities Vol. 33; no. 1; pp. 24 - 30
• Main Authors: Li, Lang, Xie, Shengming, Zhang, Junhui, Chen, Ling, Zhu, Pengjing, Yuan, Liming
• Format: Journal Article
• Language: English
• Published: Changchun Jilin University and The Editorial Department of Chemical Research in Chinese Universities 01.02.2017; Springer Nature B.V
• Subjects: Alcohols; Analytical Chemistry; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Cobalt; Column chromatography; Esters; Ethers; Fused silica; Gas chromatography; Inorganic Chemistry; Ketones; Metal-organic frameworks; Organic acids; Organic Chemistry; Organic compounds; Physical Chemistry; Thermal stability; Gas chromatography; Homochiral metal-organic framework; Chiral separation; Stationary phase
• ISSN: 1005-9040; 2210-3171
• DOI: 10.1007/s40242-017-6270-3

Homochiral metal-organic frameworks（HMOFs） have special properties, such as high surface area, fasci- nating structures and excellent chemical and thermal stability and they have broad application prospects. In this work, we reported the use of HMOF Co-L-GG（L-GG, dipeptide H-Gly-L-Glu） as the stationary phase for separating race- mates m gas chromatography. Co-L-GG coated fused silica capillary colunm（10 m×250 μm i.d.） was prepared via a dynamic coating method. Thirty racemmes belonging to different classes of organic compounds were resolved in- cluding halohydrocarbons, ketones, esters, ethers, organic acids, epoxyalkanes, alcohols and sulfoxides. When com- pared with the previously reported chiral MOFs-coated capillary colurnlls, the Co-L-GG coated column exhibited broader chiral resolution ability towards chiral compounds.