Biological reaction signal enhancement in porous silicon Bragg mirror based on quantum dots fluorescence
In this paper, we mainly study the preparation of an optical biosensor based on porous silicon（PSi） Bragg mirror and its feasibility for biological detection. The quantum dot（QD） labeled biotin was pipetted onto streptavidin functionalized PSi Bragg mirror samples, the affinity reaction between QD l...
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| Published in | Optoelectronics letters Vol. 13; no. 3; pp. 172 - 174 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
Tianjin
Tianjin University of Technology
01.05.2017
Springer Nature B.V |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1673-1905 1993-5013 |
| DOI | 10.1007/s11801-017-7034-5 |
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| Abstract | In this paper, we mainly study the preparation of an optical biosensor based on porous silicon（PSi） Bragg mirror and its feasibility for biological detection. The quantum dot（QD） labeled biotin was pipetted onto streptavidin functionalized PSi Bragg mirror samples, the affinity reaction between QD labeled biotin and streptavidin in PSi occurred, so the QDs were indirectly connected to the PSi. The fluorescence of QD enhanced the signal of biological reactions in PSi. The performance of the sensor is verified by detecting the fluorescence of the QD in PSi. Due to the fluorescence intensity of the QDs can be enhanced by PSi Bragg mirror, the sensitivity of the PSi optical biosensor will be improved. |
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| AbstractList | In this paper, we mainly study the preparation of an optical biosensor based on porous silicon（PSi） Bragg mirror and its feasibility for biological detection. The quantum dot（QD） labeled biotin was pipetted onto streptavidin functionalized PSi Bragg mirror samples, the affinity reaction between QD labeled biotin and streptavidin in PSi occurred, so the QDs were indirectly connected to the PSi. The fluorescence of QD enhanced the signal of biological reactions in PSi. The performance of the sensor is verified by detecting the fluorescence of the QD in PSi. Due to the fluorescence intensity of the QDs can be enhanced by PSi Bragg mirror, the sensitivity of the PSi optical biosensor will be improved. In this paper, we mainly study the preparation of an optical biosensor based on porous silicon (PSi) Bragg mirror and its feasibility for biological detection. The quantum dot (QD) labeled biotin was pipetted onto streptavidin functionalized PSi Bragg mirror samples, the affinity reaction between QD labeled biotin and streptavidin in PSi occurred, so the QDs were indirectly connected to the PSi. The fluorescence of QD enhanced the signal of biological reactions in PSi. The performance of the sensor is verified by detecting the fluorescence of the QD in PSi. Due to the fluorescence intensity of the QDs can be enhanced by PSi Bragg mirror, the sensitivity of the PSi optical biosensor will be improved. |
| Author | 李彦宇 贾振红 王佳佳 吕长武 |
| AuthorAffiliation | School of Physical Science and Technology, Xinjiang University, Urumqi 830046, China School of lnformation Science and Engineering, Xinjiang University, Urumqi 830046, China |
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| Notes | 12-1370/TN mirror Bragg biosensor biotin labeled detecting verified porous affinity streptavidin In this paper, we mainly study the preparation of an optical biosensor based on porous silicon（PSi） Bragg mirror and its feasibility for biological detection. The quantum dot（QD） labeled biotin was pipetted onto streptavidin functionalized PSi Bragg mirror samples, the affinity reaction between QD labeled biotin and streptavidin in PSi occurred, so the QDs were indirectly connected to the PSi. The fluorescence of QD enhanced the signal of biological reactions in PSi. The performance of the sensor is verified by detecting the fluorescence of the QD in PSi. Due to the fluorescence intensity of the QDs can be enhanced by PSi Bragg mirror, the sensitivity of the PSi optical biosensor will be improved. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 |
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| SubjectTerms | Biosensors Biotin Feasibility studies Fluorescence Lasers Optical Devices Optics Photonics Physics Physics and Astronomy Porous silicon Quantum dots 信号增强 光学生物传感器 多孔硅 布拉格反射镜 生物反应 生物素标记 荧光增强 量子点 |
| Title | Biological reaction signal enhancement in porous silicon Bragg mirror based on quantum dots fluorescence |
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