Biological reaction signal enhancement in porous silicon Bragg mirror based on quantum dots fluorescence

• Published in: Optoelectronics letters Vol. 13; no. 3; pp. 172 - 174
• Main Author: 李彦宇 贾振红 王佳佳 吕长武
• Format: Journal Article
• Language: English
• Published: Tianjin Tianjin University of Technology 01.05.2017; Springer Nature B.V
• Subjects: Biosensors; Biotin; Feasibility studies; Fluorescence; Lasers; Optical Devices; Optics; Photonics; Physics; Physics and Astronomy; Porous silicon; Quantum dots; 信号增强; 光学生物传感器; 多孔硅; 布拉格反射镜; 生物反应; 生物素标记; 荧光增强; 量子点
• ISSN: 1673-1905; 1993-5013
• DOI: 10.1007/s11801-017-7034-5

In this paper, we mainly study the preparation of an optical biosensor based on porous silicon（PSi） Bragg mirror and its feasibility for biological detection. The quantum dot（QD） labeled biotin was pipetted onto streptavidin functionalized PSi Bragg mirror samples, the affinity reaction between QD labeled biotin and streptavidin in PSi occurred, so the QDs were indirectly connected to the PSi. The fluorescence of QD enhanced the signal of biological reactions in PSi. The performance of the sensor is verified by detecting the fluorescence of the QD in PSi. Due to the fluorescence intensity of the QDs can be enhanced by PSi Bragg mirror, the sensitivity of the PSi optical biosensor will be improved.