Long-Term Follow-Up of Persistent Truncus Arteriosus: Kuwait Experience

• Published in: Medical principles and practice Vol. 21; no. 3; pp. 277 - 281
• Main Authors: Selvan, J.P., Uthaman, B., Abushaban, L., Qabandi, M.A., Al Hay, A., Al Hassan, A., Thinakarvel, M.
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland 01.01.2012
• Subjects: Aorta, Thoracic - pathology; Cardiac Surgical Procedures; Coronary Vessel Anomalies; Female; Humans; Infant; Infant, Newborn; Kuwait; Male; Original Paper; Prospective Studies; Time Factors; Treatment Outcome; Truncus Arteriosus, Persistent - diagnostic imaging; Truncus Arteriosus, Persistent - pathology; Truncus Arteriosus, Persistent - surgery; Ultrasonography; Homograft reconstruction; Conduit repair; Common arterial trunk; Persistent truncus arteriosus
• ISSN: 1011-7571; 1423-0151; 1423-0151
• DOI: 10.1159/000334590

Objective: To evaluate the long-term results of patients in Kuwait who were operated for persistent truncus arteriosus (PTA). Subjects and Methods: The following data were collected for retrospective analysis from 24 medical records of consecutive patients with PTA in Kuwait between August 1993 and August 2009: demographics, morphology, management and outcome. Major associated abnormalities included interrupted aortic arch in 1 patient and abnormal coronary artery anatomy in 2. Results: Of the 24 patients, 16 underwent total intracardiac repair. The age at operation ranged from 15 days to 5 years (mean 166.19 ± 438.63 days) and weight ranged from 2.5 to 15 kg (mean 4.3 ± 3.01 kg). The right ventricle to pulmonary artery continuity was established with aortic homograft in 11, pulmonary homograft in 4 and by implantation of a Contegra conduit in 1 patient. Four patients had moderate truncal valve regurgitation requiring concomitant truncal valve repair. After a mean follow-up period of 81.81 ± 61.58 months (range 3–166) there was no death. Eight of the 16 (50%) patients underwent redo homograft operations. One patient who had concomitant truncal valve repair subsequently underwent aortic valve replacement. Conclusion: The data showed that complete repair of PTA in the neonatal and early infancy period was the treatment with the best potential for survival. The homograft remained one of the conduits of choice to establish continuity between the right ventricle and the pulmonary artery in spite of the high incidence of conduit redo operations.