Optimization of G1 Micromixer Structure in Two-Fluid Mixing Based on CFD and Response Surface Methodology

Optimizing the structure of micromixers to improve the mixing efficiency is of great significance for chemical engineering and biology fields. In this study, an optimization of the microchannel in two liquids mixing is carried out based on computational fluid dynamics (CFD) and response surface meth...

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Published inProcesses Vol. 12; no. 1; p. 122
Main Authors Qin, Liang, Lu, Xiaoxia, Li, Lei, Han, Huan, Chai, Mingming, Yan, Xiaofang, Chen, Shuo, Wang, Hongying, Ma, Weiting
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.01.2024
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ISSN2227-9717
2227-9717
DOI10.3390/pr12010122

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Summary:Optimizing the structure of micromixers to improve the mixing efficiency is of great significance for chemical engineering and biology fields. In this study, an optimization of the microchannel in two liquids mixing is carried out based on computational fluid dynamics (CFD) and response surface methodology. Firstly, CFD simulations were performed to investigate the mixing flow field and mixing efficiency in the microchannel by considering different process and structure parameters (e.g., feed pressure p, microchannel width w). The response surface methodology was adopted to construct a fitting surface by CFD discrete working conditions. Then, an optimized microchannel width w was searched using the parallel particle swarm optimization (PPSO) algorithm from the response surface. Lastly, the searched optimum was validated by CFD simulation again, and the final result showed that the predicted mixing efficiency from the response surface model is well confirmed by CFD simulation. On average, the new optimized microchannel width of 1.634 mm performs higher flow flux and mixing efficiency than the original width of 1.5 mm, increasing 13.51% and 2.45%, respectively.
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ISSN:2227-9717
2227-9717
DOI:10.3390/pr12010122