A Neural Probe With Up to 966 Electrodes and Up to 384 Configurable Channels in 0.13 $\mu$m SOI CMOS

• Published in: IEEE transactions on biomedical circuits and systems Vol. 11; no. 3; pp. 510 - 522
• Main Authors: Mora Lopez, Carolina, Putzeys, Jan, Raducanu, Bogdan Cristian, Ballini, Marco, Wang, Shiwei, Andrei, Alexandru, Rochus, Veronique, Vandebriel, Roeland, Severi, Simone, Van Hoof, Chris, Musa, Silke, Van Helleputte, Nick, Yazicioglu, Refet Firat, Mitra, Srinjoy
• Format: Journal Article
• Language: English
• Published: United States The Institute of Electrical and Electronics Engineers, Inc. (IEEE) 01.06.2017
• Subjects: Brain; Brain - physiology; CMOS; Crosstalk; Electrodes; High resolution; Humans; Neurons - physiology; Neurophysiology - instrumentation; Power consumption; Probes; Recording; Silicon; Surgical implants
• ISSN: 1932-4545; 1940-9990; 1940-9990
• DOI: 10.1109/TBCAS.2016.2646901

In vivo recording of neural action-potential and local-field-potential signals requires the use of high-resolution penetrating probes. Several international initiatives to better understand the brain are driving technology efforts towards maximizing the number of recording sites while minimizing the neural probe dimensions. We designed and fabricated (0.13- μm SOI Al CMOS) a 384-channel configurable neural probe for large-scale in vivo recording of neural signals. Up to 966 selectable active electrodes were integrated along an implantable shank (70 μm wide, 10 mm long, 20  μm thick), achieving a crosstalk of [Formula: see text] dB. The probe base (5 × 9 mm ) implements dual-band recording and a 171.6 Mbps digital interface. Measurement results show a total input-referred noise of 6.4 μ V and a total power consumption of 49.1  μW/channel.