Stochastic initiation of DNA replication across the human genome
Wang et al. (2021) comprehensively map DNA replication initiation events across the human genome using single-molecule optical resolution mapping and find that initiation events are randomly distributed across broad initiation zones that are only utilized in a stochastic fashion across a population...
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| Published in | Molecular cell Vol. 81; no. 14; pp. 2873 - 2874 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
15.07.2021
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| Online Access | Get full text |
| ISSN | 1097-2765 1097-4164 1097-4164 |
| DOI | 10.1016/j.molcel.2021.06.022 |
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| Summary: | Wang et al. (2021) comprehensively map DNA replication initiation events across the human genome using single-molecule optical resolution mapping and find that initiation events are randomly distributed across broad initiation zones that are only utilized in a stochastic fashion across a population of cells.Wang et al. (2021) comprehensively map DNA replication initiation events across the human genome using single-molecule optical resolution mapping and find that initiation events are randomly distributed across broad initiation zones that are only utilized in a stochastic fashion across a population of cells. |
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| Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Commentary-3 content type line 23 |
| ISSN: | 1097-2765 1097-4164 1097-4164 |
| DOI: | 10.1016/j.molcel.2021.06.022 |