Seasonal variation of chemical profile of Ruta graveolens extracts and biological activity against Fusarium oxysporum, Fusarium proliferatum and Stemphylium vesicarium

• Published in: Biochemical systematics and ecology Vol. 95; p. 104223
• Main Authors: Reyes-Vaquero, Lorena, Bueno, Monica, Ventura-Aguilar, Rosa Isela, Aguilar-Guadarrama, A. Berenice, Robledo, Norma, Sepúlveda-Jiménez, Gabriela, Vanegas-Espinoza, Pablo Emilio, Ibáñez, Elena, Del Villar-Martínez, Alma Angélica
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.04.2021
• Subjects: absorbance; Alkaloids; Antifungal activity; antifungal properties; chemotaxonomy; ecology; Fatty acids; Fusarium oxysporum; Fusarium proliferatum; growth retardation; Principal component analysis; psoralens; Ruta graveolens; seasonal variation; Stemphylium vesicarium; terpenoids; Alkaloids; Antifungal activity; Fatty acids; Principal component analysis
• ISSN: 0305-1978; 1873-2925
• DOI: 10.1016/j.bse.2021.104223

Ruta graveolens L. is a plant of agricultural interest due to its biological activity against phytopathogenic microorganism. This activity has been attributed to the presence of alkaloids, furanocoumarins, terpenes and fatty acids. The accumulation of these compounds is affected by environmental factors. The aim of this work was to analyze the seasonal variation the chemical profile of rue and to evaluate the biological activity against phytopathogenic fungi. Extracts were obtained in January, April, June and September 2017, chemically characterized by GC-MS. The antifungal activity was determined by absorbance, four concentrations were evaluated: 4, 8, 16 and 32 mg/mL. In extracts from the aerial parts, fatty acids were the most abundant group in the January sample (29.7%), and alkaloids in the April and June (27.7%) samples. In extracts from the roots, alkaloids were the most abundant group in the four collections. The highest percentage of growth inhibition on Fusarium and Stemphylium was obtained with the extracts of the January sample. Ruta graveolens can be considered an alternative for the management of phytopathogenic fungi of crops of economic importance. [Display omitted] •Ruta graveolens is a plant that has biological activity against phytopathogenic fungi.•Alkaloids were the most abundant group in the roots extracts of R. graveolens.•The accumulation of fatty acids and alkaloids was influenced by the season.•The antifungal activity was maximum inhibition values between 69 and 73%.