The accuracy of self-reported family history in glaucoma in Brazil

• Published in: International ophthalmology Vol. 44; no. 1; p. 263
• Main Authors: de Almeida Figueiredo, Ana Galrão, Nogueira, Isadora Ferro, de Moura Santos Pereira Ferraz Baptista, Liane, Foganholo, Jady, Iguma, Camila Ishii, Abe, Ricardo Yuji
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 24.06.2024; Springer Nature B.V
• Subjects: Accuracy; Adult; Aged; Brazil - epidemiology; Confidence intervals; Cross-Sectional Studies; Female; Genetics; Glaucoma; Glaucoma - diagnosis; Glaucoma - epidemiology; Glaucoma - genetics; Humans; Male; Medical History Taking - statistics & numerical data; Medicine; Medicine & Public Health; Middle Aged; Ophthalmology; Original Paper; Regression analysis; Reproducibility of Results; Risk Factors; Self Report; Statistical analysis; Brazil; Family history; Primary open angle glaucoma; Risk factor
• ISSN: 1573-2630; 0165-5701; 1573-2630
• DOI: 10.1007/s10792-024-03193-8

Purpose To evaluate the accuracy of a positive self-reported glaucoma family history. Material and methods Cross-sectional study. Each subject was asked if they had a first-degree relative diagnosed with glaucoma. If their answer was affirmative, the relative was invited to attend on ophthalmic evaluation and underwent complementary exams to confirm or exclude the glaucoma diagnosis. Only one relative was included per subject. Results We included 204 subjects in the study (102 subjects and their respective relatives). The accuracy of family history of glaucoma was 76.96% of the cases. In the univariable analysis, subjects with college degree had 2.34 [( P  = 0.010; 95% confidence interval (CI) 1.18–4.63)], with higher family income 3.72 ( P  = 0.003; 95% CI 1.57–8.85) and those with health insurance 3.42 ( P  = 0.001; 95% CI 1.67–6.98) more chances to have a true positive family history for glaucoma. In the multivariable logistic regression analysis, none of the variables presented significant association. Conclusion Around 24% of patients may not provide reliable information about family history for glaucoma. When asking about a glaucoma family history, clinicians should consider the real accuracy of this self-reported data.