Application of Microwave Activation Techniques to the N-Alkenyl Protection of Lactams

Rapid and facile, syntheses of N-alkenyl lactam series via condensation between lactams and a variety of aldehydes such as n-propanal, isobutanal, n-butanal, n-hexanal, n-octanal and phenylacetaldehyde were studied under microwave or conventional heating. Various solid catalysts and solvents were ex...

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Bibliographic Details
Published inBulletin of the Korean Chemical Society Vol. 27; no. 2; pp. 286 - 290
Main Authors Kim, KW, Ahn, HS, Lee, HJ, Song, SA, Kim, CG, Kwon, TW
Format Journal Article
LanguageEnglish
Published WEINHEIM Wiley 20.02.2006
대한화학회
Subjects
Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
화학
ORGANIC-SYNTHESIS
ENHANCED KNOEVENAGEL CONDENSATION
ASYMMETRIC-SYNTHESIS
ACID
aldehyde condensation
microwave irradiation
N-alkenylation
pyrrolidin-2-one
SYNTHON
DERIVATIVES
ethyl pyroglutamate
Online AccessGet full text
ISSN0253-2964
1229-5949
1229-5949
DOI10.5012/bkcs.2006.27.2.286

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Summary:Rapid and facile, syntheses of N-alkenyl lactam series via condensation between lactams and a variety of aldehydes such as n-propanal, isobutanal, n-butanal, n-hexanal, n-octanal and phenylacetaldehyde were studied under microwave or conventional heating. Various solid catalysts and solvents were examined to maximize the yields of condensation reactions.
Bibliography:G704-000067.2006.27.2.034
ISSN:0253-2964
1229-5949
1229-5949
DOI:10.5012/bkcs.2006.27.2.286