Role of Glutathione-S-Transferase Polymorphism on Arsenic-Induced Protein Carbonylation and Urinary Deoxy Guanosine Status

Oxidative stress is significantly associated with chronic arsenic exposure in persons exposed to moderate-to-high level of environmental arsenic. However, the response varies widely among persons within similar exposure level. To study whether Glutathione-S-Transferase (GST) gene polymorphism plays...

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Published inExposure and health Vol. 12; no. 3; pp. 539 - 546
Main Authors Chanda, Sarmishtha, Roy, Jayashree, Guha Mazumder, Debendranath, Chakraborty, Tushar
Format Journal Article
LanguageEnglish
Published Dordrecht Springer Netherlands 01.09.2020
Springer Nature B.V
Subjects
8-Hydroxydeoxyguanosine
Aquatic Pollution
Arsenic
Carbonyls
Creatinine
DNA damage
DNA methylation
Drinking water
Earth and Environmental Science
Environment
Environmental Health
Enzymes
Exposure
Gene polymorphism
Glutathione
Glutathione transferase
GSTM1 protein
GSTT1 protein
Laboratory animals
Metabolism
Nonparametric statistics
Original Paper
Oxidation
Oxidative stress
Pollution
Polymorphism
Proteins
Urine
Waste Water Technology
Water and Health
Water Management
Water Pollution Control
Water Quality/Water Pollution
West Bengal India
United States > US
Baltimore Maryland
India
Protein carbonylation
GST polymorphism
Arsenic
Oxidative DNA damage
Online AccessGet full text
ISSN2451-9766
2451-9685
DOI10.1007/s12403-019-00319-7

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Abstract Oxidative stress is significantly associated with chronic arsenic exposure in persons exposed to moderate-to-high level of environmental arsenic. However, the response varies widely among persons within similar exposure level. To study whether Glutathione-S-Transferase (GST) gene polymorphism plays any pivotal role in this variation, total number of 115 chronic arsenic-exposed study subjects without arsenic-induced cancer from School of Tropical Medicine, Kolkata and from arsenic-exposed districts of West Bengal were recruited for this study. Concentration of arsenic in their urine and water, extent of clinical manifestation, GST status and protein carbonylation, and 8-oxo-2′-deoxyguanosine status were determined. Genetic polymorphism of GSTM1 and T1 were significantly associated ( p  < 0.05) with degree of protein carbonylation and 8-oxo-2′-deoxyguanosine in moderate-to-high degree of arsenic exposure groups. Persons having null genotype have significantly increased level of protein carbonylation and 8-oxo-2′-deoxyguanosine in comparison to persons with GSTM1 or GSTT1 non-null genotype of the same arsenic exposure group. Degree of protein carbonylation and urinary 8-oxo-2-deoxyguanosine is positively correlated with GST null genotype.
AbstractList Oxidative stress is significantly associated with chronic arsenic exposure in persons exposed to moderate-to-high level of environmental arsenic. However, the response varies widely among persons within similar exposure level. To study whether Glutathione-S-Transferase (GST) gene polymorphism plays any pivotal role in this variation, total number of 115 chronic arsenic-exposed study subjects without arsenic-induced cancer from School of Tropical Medicine, Kolkata and from arsenic-exposed districts of West Bengal were recruited for this study. Concentration of arsenic in their urine and water, extent of clinical manifestation, GST status and protein carbonylation, and 8-oxo-2′-deoxyguanosine status were determined. Genetic polymorphism of GSTM1 and T1 were significantly associated (p < 0.05) with degree of protein carbonylation and 8-oxo-2′-deoxyguanosine in moderate-to-high degree of arsenic exposure groups. Persons having null genotype have significantly increased level of protein carbonylation and 8-oxo-2′-deoxyguanosine in comparison to persons with GSTM1 or GSTT1 non-null genotype of the same arsenic exposure group. Degree of protein carbonylation and urinary 8-oxo-2-deoxyguanosine is positively correlated with GST null genotype.
Oxidative stress is significantly associated with chronic arsenic exposure in persons exposed to moderate-to-high level of environmental arsenic. However, the response varies widely among persons within similar exposure level. To study whether Glutathione-S-Transferase (GST) gene polymorphism plays any pivotal role in this variation, total number of 115 chronic arsenic-exposed study subjects without arsenic-induced cancer from School of Tropical Medicine, Kolkata and from arsenic-exposed districts of West Bengal were recruited for this study. Concentration of arsenic in their urine and water, extent of clinical manifestation, GST status and protein carbonylation, and 8-oxo-2′-deoxyguanosine status were determined. Genetic polymorphism of GSTM1 and T1 were significantly associated ( p  < 0.05) with degree of protein carbonylation and 8-oxo-2′-deoxyguanosine in moderate-to-high degree of arsenic exposure groups. Persons having null genotype have significantly increased level of protein carbonylation and 8-oxo-2′-deoxyguanosine in comparison to persons with GSTM1 or GSTT1 non-null genotype of the same arsenic exposure group. Degree of protein carbonylation and urinary 8-oxo-2-deoxyguanosine is positively correlated with GST null genotype.
Author Roy, Jayashree
Guha Mazumder, Debendranath
Chakraborty, Tushar
Chanda, Sarmishtha
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Cites_doi 10.1186/s41021-051-0023-7
10.1016/j.taap.2009.11.007
10.1016/j.ijdevneu.2011.06.006
10.1158/0008-5472.CAN-08-3418
10.1016/0009-2797(93)90086-E
10.1093/toxsci/kfj030
10.1016/S0076-6879(99)00118-4
10.1016/S1383-5742(97)00005-7
10.1038/s41598-017-18925-3
10.1289/ehp.7401
10.1371/journal.pgen.1003640
10.1080/01926230600824926
10.1146/annurev-arplant-042809-112152
10.1038/srep02704
10.1016/j.taap.2003.10.021
10.1002/jbt.20416
10.1080/15287390600755240
10.1177/0748233710377775
10.1007/s12011-016-0810-4
10.1155/2015/892579
10.1023/B:BIOM.0000045740.52182.9d
10.1097/00008469-200506000-00014
10.1016/jmrgentox.2008.09.021
10.1039/B513652K
10.1146/annurev.pharmtox.37.1.397
10.1080/15563650701354119
10.1016/j.freeradbiomed.2010.02.004
10.1097/JOM.0000000000000166
10.1385/BTER:100:1:039
10.1289/ehp.1002471
10.1007/s11010-005-8227-y
10.1016/j.envint.2017.12.017
10.1016/B978-008043648-7/50031-5
10.1289/ehp.9734
10.1023/A:1015927406142
10.1289/ehp.9152
10.1016/j.taap.2010.10.025
10.1186/1476-069X-6-39
10.1158/1055-9965.EPI-05-0306
10.1177/0748233708093355
10.22506/ti/2015/v22/i3/137632
10.1006/bbrc.2001.5551
10.1016/j.plaphy.2009.05.007
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References Aposhian (CR3) 1997; 37
Vahter (CR36) 1999; II
Hays, Srinivasan, Witten, Carter, Lantz (CR18) 2006; 34
Winterbourn, Buss (CR38) 1999; 300
Yamauchi, Aminaka, Yoshida (CR42) 2004; 198
Bhattacharya, Paul, Banerjee (CR5) 2013; 3
Kile, Houseman, Rodrigues (CR21) 2005; 14
Allen, Rana (CR2) 2004; 100
Zipprich, Terry, Liao (CR44) 2009; 69
Litwin, Bocer, Dziadkowiec, Wysocki (CR23) 2013; 9
Breton, Kile, Catalano (CR6) 2007; 6
Han, Song, Cui, Xia, Ma (CR16) 2011; 29
Xu, Rui, Yan (CR40) 2016; 176
Engström, Broberg, Concha (CR12) 2007; 115
Thompson (CR34) 1993; 88
Ruiz Ramos, Lopez-Carillo, Rios-Perez, De Vizcaya-Ruiz, Cebrian (CR32) 2009; 674
Harper, Liu, Hall (CR17) 2014; 56
Steinmaus, Moore, Ship (CR33) 2007; 70
Chanda, Dasgupta, GuhaMazumder (CR8) 2006; 89
Mondal, Paria, Majumder (CR28) 2005; 14
Toora, Rajagopal (CR35) 2002; 40
Agusa, Fujihara, Minh (CR1) 2010; 242
Whittakar, Fowler (CR37) 2011; 254
Bera, Rana, Das (CR4) 2010; 26
Chanda, Dasgupta, Guhamazumder, Chaudhuri, Ganguli (CR9) 2015; 22
Kessel, Liu, Xu, Santella, Hei (CR20) 2002; 234–235
Chiou, Hsueh, Hsieh (CR10) 1997; 386
Fowler, Whittakar, Lipsky, Wang, Chen (CR15) 2004; 17
Paul, Majumder, Giri (CR30) 2015; 37
Luo, Li, Gao (CR24) 2017; 8
Kubota, Kunito, Agusa (CR22) 2006; 8
CR29
Wong, Kuo, Hsu (CR39) 2005; 113
Mishra, Flora (CR27) 2008; 24
Burgess, Meza, Josyula (CR7) 2007; 45
Engstrom, Vahter, Johansson (CR14) 2010; 48
Minatel, Sage, Anderson (CR26) 2018; 112
Hsu, Wu, Wang (CR19) 2015
CR41
Engström, Vahter, Mlakar (CR13) 2011; 119
Zhao, McGrath, Meharg (CR43) 2010; 61
Ding, Hudson, Liu (CR11) 2005; 279
McCarty, Chen, Quamrruzzaman (CR25) 2007; 115
Rana, Bera, Das (CR31) 2012; 26
R Kubota (319_CR22) 2006; 8
ML Kile (319_CR21) 2005; 14
HV Aposhian (319_CR3) 1997; 37
KS Engstrom (319_CR14) 2010; 48
M Xu (319_CR40) 2016; 176
T Rana (319_CR31) 2012; 26
S Paul (319_CR30) 2015; 37
DJ Thompson (319_CR34) 1993; 88
MH Whittakar (319_CR37) 2011; 254
D Mishra (319_CR27) 2008; 24
HY Chiou (319_CR10) 1997; 386
M Vahter (319_CR36) 1999; II
319_CR29
BA Fowler (319_CR15) 2004; 17
I Litwin (319_CR23) 2013; 9
R Ruiz Ramos (319_CR32) 2009; 674
319_CR41
H Yamauchi (319_CR42) 2004; 198
AM Hays (319_CR18) 2006; 34
KS Engström (319_CR12) 2007; 115
BC Minatel (319_CR26) 2018; 112
KS Engström (319_CR13) 2011; 119
CV Breton (319_CR6) 2007; 6
C Steinmaus (319_CR33) 2007; 70
ZJ Han (319_CR16) 2011; 29
T Allen (319_CR2) 2004; 100
S Chanda (319_CR9) 2015; 22
A Bera (319_CR4) 2010; 26
L Luo (319_CR24) 2017; 8
LI Hsu (319_CR19) 2015
BD Toora (319_CR35) 2002; 40
FJ Zhao (319_CR43) 2010; 61
M Kessel (319_CR20) 2002; 234–235
BC Mondal (319_CR28) 2005; 14
JL Burgess (319_CR7) 2007; 45
W Ding (319_CR11) 2005; 279
RH Wong (319_CR39) 2005; 113
T Agusa (319_CR1) 2010; 242
KN Harper (319_CR17) 2014; 56
P Bhattacharya (319_CR5) 2013; 3
CC Winterbourn (319_CR38) 1999; 300
S Chanda (319_CR8) 2006; 89
KM McCarty (319_CR25) 2007; 115
J Zipprich (319_CR44) 2009; 69
References_xml – volume: 37
  start-page: 23
  year: 2015
  ident: CR30
  article-title: Genetic susceptibility to arsenic induced skin lesions and health effects: a review
  publication-title: Genes Environ
  doi: 10.1186/s41021-051-0023-7
– volume: 242
  start-page: 352
  year: 2010
  end-page: 362
  ident: CR1
  article-title: Genetic polymorphisms in glutathione S-transferase (GST) superfamily and arsenic metabolism in residents of the Red River Delta, Vietnam
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1016/j.taap.2009.11.007
– volume: 29
  start-page: 673
  year: 2011
  end-page: 680
  ident: CR16
  article-title: Oxidative stress is implicated in arsenic induced neural tube defects in chick embryos
  publication-title: Int J Dev Neurosci
  doi: 10.1016/j.ijdevneu.2011.06.006
– volume: 69
  start-page: 2966
  issue: 7
  year: 2009
  end-page: 2972
  ident: CR44
  article-title: Plasma protein carbonyls and breast cancer risk in sisters discordant for breast cancer from the New York Site of the Breast Cancer Family Registry
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-08-3418
– volume: 88
  start-page: 89
  year: 1993
  end-page: 114
  ident: CR34
  article-title: A chemical hypothesis for arsenic methylation in mammals
  publication-title: Chem Biol Interact
  doi: 10.1016/0009-2797(93)90086-E
– volume: 89
  start-page: 431
  year: 2006
  end-page: 437
  ident: CR8
  article-title: DNA hypermethylation of promoter of gene p53 and p16 in arsenic-exposed people with and without malignancy
  publication-title: Toxicol Sci
  doi: 10.1093/toxsci/kfj030
– volume: 300
  start-page: 106
  year: 1999
  end-page: 111
  ident: CR38
  article-title: Protein carbonyl measurement by enzyme-linked immunosorbent assay
  publication-title: Methods Enzymol
  doi: 10.1016/S0076-6879(99)00118-4
– volume: 386
  start-page: 197
  year: 1997
  end-page: 207
  ident: CR10
  article-title: Arsenic methylation capacity, body retention and null genotypes of glutathione S-transferase M1 and T1 among current arsenic-exposed residents in Taiwan
  publication-title: Mutat Res
  doi: 10.1016/S1383-5742(97)00005-7
– volume: 8
  start-page: 413
  year: 2017
  ident: CR24
  article-title: Association between arsenic metabolism gene polymorphisms and arsenic-induced skin lesions in individuals exposed to high-dose inorganic arsenic in northwest China
  publication-title: Sci Rep
  doi: 10.1038/s41598-017-18925-3
– volume: 113
  start-page: 1386
  issue: 10
  year: 2005
  end-page: 1390
  ident: CR39
  article-title: Increased levels of 8-hydroxy-2′-deoxyguanosine attributable to carcinogenic metal exposure among school children
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.7401
– volume: 9
  start-page: e1003640
  issue: 7
  year: 2013
  ident: CR23
  article-title: Oxidative stress and replication independent DNA breakage induced by arsenic in
  publication-title: PLoS Genet
  doi: 10.1371/journal.pgen.1003640
– volume: 34
  start-page: 396
  issue: 4
  year: 2006
  end-page: 404
  ident: CR18
  article-title: Arsenic and cigarette smoke synergistically increase DNA oxidation in the lung
  publication-title: Toxicol Pathol
  doi: 10.1080/01926230600824926
– volume: 61
  start-page: 535
  year: 2010
  end-page: 559
  ident: CR43
  article-title: Arsenic as a food chain contaminant: mechanisms of plant uptake and metabolism and mitigation strategies
  publication-title: Annu Rev Plant Biol
  doi: 10.1146/annurev-arplant-042809-112152
– volume: 3
  start-page: 2704
  year: 2013
  ident: CR5
  article-title: Functional compensation of glutathione S transferase M1 (GSTM1) null by another GST superfamily member, GSTM2
  publication-title: Sci Rep
  doi: 10.1038/srep02704
– volume: 198
  start-page: 291
  year: 2004
  end-page: 296
  ident: CR42
  article-title: Evaluation of DNA damage in patients with arsenic poisoning: urinary 8-hydroxydeoxyguanine
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1016/j.taap.2003.10.021
– ident: CR29
– volume: 26
  start-page: 109
  year: 2012
  end-page: 116
  ident: CR31
  article-title: Meta bolic adaptations to arsenic-induced oxidative stress in male Wister rats
  publication-title: J Biochem Mol Toxicol
  doi: 10.1002/jbt.20416
– volume: 70
  start-page: 159
  year: 2007
  end-page: 170
  ident: CR33
  article-title: Genetic polymorphisms in MTHFR 677 and 1298, GSTM1 and T1, and metabolism of arsenic
  publication-title: J Toxicol Environ Health Part A
  doi: 10.1080/15287390600755240
– volume: 26
  start-page: 709
  year: 2010
  end-page: 716
  ident: CR4
  article-title: Ground water arsenic contamination in West Bengal, India: a risk of sub-clinical toxicity in cattle as evident by correlation between arsenic exposure, excretion and deposition
  publication-title: Toxicol Ind Health
  doi: 10.1177/0748233710377775
– volume: 176
  start-page: 154
  year: 2016
  end-page: 175
  ident: CR40
  article-title: Oxidative damage induced by arsenic in mice or rats: a systemic review and meta analysis
  publication-title: Biol Trace Elem Res
  doi: 10.1007/s12011-016-0810-4
– year: 2015
  ident: CR19
  article-title: Association of environmental arsenic exposure, genetic polymorphisms of susceptibility genes, and skin cancers in Taiwan
  publication-title: Biomed Res Int
  doi: 10.1155/2015/892579
– volume: 17
  start-page: 567
  year: 2004
  end-page: 568
  ident: CR15
  article-title: Oxidative stress induced by lead, cadmium and arsenic mixtures: 30-day, 90-day, and 180 day drinking water studies in rats: an overview
  publication-title: Biometals
  doi: 10.1023/B:BIOM.0000045740.52182.9d
– volume: 14
  start-page: 281
  year: 2005
  end-page: 284
  ident: CR28
  article-title: Glutathione-S-transferase M1 and T1 null genotype frequency in chronic myeloid leukemia
  publication-title: Eurp J Cancer Prev
  doi: 10.1097/00008469-200506000-00014
– volume: 674
  start-page: 109
  issue: 1–2
  year: 2009
  end-page: 115
  ident: CR32
  article-title: Sodium arsenite induces ROS generation, DNA oxidative damage, HO-1 and c-Myc proteins, NF-kappa B activation and cell proliferation in human breast cancer MCF-7 cells
  publication-title: Mutat Res
  doi: 10.1016/jmrgentox.2008.09.021
– volume: 8
  start-page: 293
  year: 2006
  end-page: 299
  ident: CR22
  article-title: Urinary 8-hydroxy-2′-deoxyguanosine in inhabitants chronically exposed to arsenic in groundwater in Cambodia
  publication-title: J Environ Monit
  doi: 10.1039/B513652K
– volume: 37
  start-page: 397
  year: 1997
  end-page: 419
  ident: CR3
  article-title: Enzymatic methylation of arsenic species and other new approaches to arsenic
  publication-title: Annu Rev Pharm Toxicol
  doi: 10.1146/annurev.pharmtox.37.1.397
– volume: 45
  start-page: 490
  year: 2007
  end-page: 498
  ident: CR7
  article-title: Environmental arsenic exposure and urinary 8-OHdG in Arizona and Sonora
  publication-title: Clin Toxicol (Phila)
  doi: 10.1080/15563650701354119
– volume: 48
  start-page: 1211
  issue: 9
  year: 2010
  end-page: 1217
  ident: CR14
  article-title: Chronic exposure to cadmium and arsenic strongly influences concentrations of 8-oxo-7,8-dihydro-2’-deoxyguanosine in urine
  publication-title: Free Radic Biol Med
  doi: 10.1016/j.freeradbiomed.2010.02.004
– volume: 56
  start-page: 652
  year: 2014
  end-page: 658
  ident: CR17
  article-title: A dose response study of arsenic exposure and markers of oxidative damage in Bangladesh
  publication-title: J Occup Environ Med
  doi: 10.1097/JOM.0000000000000166
– volume: 100
  start-page: 39
  year: 2004
  end-page: 48
  ident: CR2
  article-title: Effect of arsenic (AsIII) on glutathione-dependent enzymes in liver and kidney of the freshwater fish
  publication-title: Biol Trace Elem Res
  doi: 10.1385/BTER:100:1:039
– volume: 119
  start-page: 182
  year: 2011
  end-page: 188
  ident: CR13
  article-title: Polymorphisms in Arsenic(+III oxidation state) methyltransferase (AS3MT) predict gene expression of AS3MT as well as arsenic metabolism
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.1002471
– volume: 40
  start-page: 352
  issue: 3
  year: 2002
  end-page: 354
  ident: CR35
  article-title: Measurement of creatinine by Jaffe's reaction-determination of concentration of sodium hydroxide required for maximum color development in standard, urine and protein free filtrate of serum
  publication-title: Indian J Exp Biol
– volume: 279
  start-page: 105
  year: 2005
  end-page: 112
  ident: CR11
  article-title: Inorganic arsenic compounds cause oxidative damage to DNA and protein by inducing ROS and RNS generation in human keratinocytes
  publication-title: Mol Cell Biochem
  doi: 10.1007/s11010-005-8227-y
– volume: 112
  start-page: 183
  year: 2018
  end-page: 197
  ident: CR26
  article-title: Environmental arsenic exposure: from genetic susceptibility to pathogenesis
  publication-title: Environ Int
  doi: 10.1016/j.envint.2017.12.017
– volume: II
  start-page: 267
  year: 1999
  end-page: 275
  ident: CR36
  article-title: Variation in human metabolism of arsenic
  publication-title: Arsenic Exposure and Health Effects Edition
  doi: 10.1016/B978-008043648-7/50031-5
– volume: 115
  start-page: 599
  year: 2007
  end-page: 605
  ident: CR12
  article-title: Genetic polymorphisms influencing arsenic metabolism: evidence from Argentina
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.9734
– volume: 234–235
  start-page: 301
  issue: 1–2
  year: 2002
  end-page: 308
  ident: CR20
  article-title: Arsenic induces oxidative DNA damage in mammalian cells
  publication-title: Mol Cell Biochem
  doi: 10.1023/A:1015927406142
– volume: 115
  start-page: 341
  year: 2007
  end-page: 345
  ident: CR25
  article-title: Arsenic methylation, GSTT1, GSTM1, GSTP1 polymorphisms, and skin lesions
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.9152
– volume: 254
  start-page: 154
  year: 2011
  end-page: 166
  ident: CR37
  article-title: Exposure to Pb, Cd and As mixtures potentiates the production of oxidative stress precursors: 30-day, 90-day, and 180-day drinking water studies in rats
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1016/j.taap.2010.10.025
– volume: 6
  start-page: 39
  year: 2007
  ident: CR6
  article-title: GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures study
  publication-title: Environ Health
  doi: 10.1186/1476-069X-6-39
– volume: 14
  start-page: 2419
  year: 2005
  end-page: 2426
  ident: CR21
  article-title: Toenail arsenic concentrations, GSTT1 gene polymorphisms, and arsenic exposure from drinking water
  publication-title: Cancer Epidemiol Biomarkers Prev
  doi: 10.1158/1055-9965.EPI-05-0306
– ident: CR41
– volume: 24
  start-page: 247
  year: 2008
  end-page: 256
  ident: CR27
  article-title: Differential oxidative stress and DNA damage in rat brain regions and blood following chronic arsenic exposure
  publication-title: Toxicol Ind Health
  doi: 10.1177/0748233708093355
– volume: 22
  start-page: 96
  issue: 3
  year: 2015
  end-page: 100
  ident: CR9
  article-title: Role of glutathione-S-transferase polymorphism in arsenic induced DNA hypermethylation
  publication-title: Toxicol Ins
  doi: 10.22506/ti/2015/v22/i3/137632
– volume: 26
  start-page: 109
  year: 2012
  ident: 319_CR31
  publication-title: J Biochem Mol Toxicol
  doi: 10.1002/jbt.20416
– volume: 22
  start-page: 96
  issue: 3
  year: 2015
  ident: 319_CR9
  publication-title: Toxicol Ins
  doi: 10.22506/ti/2015/v22/i3/137632
– volume: 29
  start-page: 673
  year: 2011
  ident: 319_CR16
  publication-title: Int J Dev Neurosci
  doi: 10.1016/j.ijdevneu.2011.06.006
– volume: II
  start-page: 267
  year: 1999
  ident: 319_CR36
  publication-title: Arsenic Exposure and Health Effects Edition
  doi: 10.1016/B978-008043648-7/50031-5
– volume: 14
  start-page: 2419
  year: 2005
  ident: 319_CR21
  publication-title: Cancer Epidemiol Biomarkers Prev
  doi: 10.1158/1055-9965.EPI-05-0306
– volume: 9
  start-page: e1003640
  issue: 7
  year: 2013
  ident: 319_CR23
  publication-title: PLoS Genet
  doi: 10.1371/journal.pgen.1003640
– ident: 319_CR41
  doi: 10.1006/bbrc.2001.5551
– volume: 24
  start-page: 247
  year: 2008
  ident: 319_CR27
  publication-title: Toxicol Ind Health
  doi: 10.1177/0748233708093355
– volume: 674
  start-page: 109
  issue: 1–2
  year: 2009
  ident: 319_CR32
  publication-title: Mutat Res
  doi: 10.1016/jmrgentox.2008.09.021
– volume: 198
  start-page: 291
  year: 2004
  ident: 319_CR42
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1016/j.taap.2003.10.021
– volume: 61
  start-page: 535
  year: 2010
  ident: 319_CR43
  publication-title: Annu Rev Plant Biol
  doi: 10.1146/annurev-arplant-042809-112152
– volume: 112
  start-page: 183
  year: 2018
  ident: 319_CR26
  publication-title: Environ Int
  doi: 10.1016/j.envint.2017.12.017
– volume: 100
  start-page: 39
  year: 2004
  ident: 319_CR2
  publication-title: Biol Trace Elem Res
  doi: 10.1385/BTER:100:1:039
– volume: 115
  start-page: 341
  year: 2007
  ident: 319_CR25
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.9152
– volume: 26
  start-page: 709
  year: 2010
  ident: 319_CR4
  publication-title: Toxicol Ind Health
  doi: 10.1177/0748233710377775
– volume: 6
  start-page: 39
  year: 2007
  ident: 319_CR6
  publication-title: Environ Health
  doi: 10.1186/1476-069X-6-39
– volume: 34
  start-page: 396
  issue: 4
  year: 2006
  ident: 319_CR18
  publication-title: Toxicol Pathol
  doi: 10.1080/01926230600824926
– volume: 300
  start-page: 106
  year: 1999
  ident: 319_CR38
  publication-title: Methods Enzymol
  doi: 10.1016/S0076-6879(99)00118-4
– volume: 242
  start-page: 352
  year: 2010
  ident: 319_CR1
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1016/j.taap.2009.11.007
– volume: 88
  start-page: 89
  year: 1993
  ident: 319_CR34
  publication-title: Chem Biol Interact
  doi: 10.1016/0009-2797(93)90086-E
– volume: 17
  start-page: 567
  year: 2004
  ident: 319_CR15
  publication-title: Biometals
  doi: 10.1023/B:BIOM.0000045740.52182.9d
– volume: 3
  start-page: 2704
  year: 2013
  ident: 319_CR5
  publication-title: Sci Rep
  doi: 10.1038/srep02704
– volume: 70
  start-page: 159
  year: 2007
  ident: 319_CR33
  publication-title: J Toxicol Environ Health Part A
  doi: 10.1080/15287390600755240
– volume: 386
  start-page: 197
  year: 1997
  ident: 319_CR10
  publication-title: Mutat Res
  doi: 10.1016/S1383-5742(97)00005-7
– volume: 176
  start-page: 154
  year: 2016
  ident: 319_CR40
  publication-title: Biol Trace Elem Res
  doi: 10.1007/s12011-016-0810-4
– volume: 37
  start-page: 397
  year: 1997
  ident: 319_CR3
  publication-title: Annu Rev Pharm Toxicol
  doi: 10.1146/annurev.pharmtox.37.1.397
– year: 2015
  ident: 319_CR19
  publication-title: Biomed Res Int
  doi: 10.1155/2015/892579
– volume: 8
  start-page: 413
  year: 2017
  ident: 319_CR24
  publication-title: Sci Rep
  doi: 10.1038/s41598-017-18925-3
– volume: 119
  start-page: 182
  year: 2011
  ident: 319_CR13
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.1002471
– volume: 8
  start-page: 293
  year: 2006
  ident: 319_CR22
  publication-title: J Environ Monit
  doi: 10.1039/B513652K
– volume: 56
  start-page: 652
  year: 2014
  ident: 319_CR17
  publication-title: J Occup Environ Med
  doi: 10.1097/JOM.0000000000000166
– volume: 113
  start-page: 1386
  issue: 10
  year: 2005
  ident: 319_CR39
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.7401
– volume: 279
  start-page: 105
  year: 2005
  ident: 319_CR11
  publication-title: Mol Cell Biochem
  doi: 10.1007/s11010-005-8227-y
– volume: 254
  start-page: 154
  year: 2011
  ident: 319_CR37
  publication-title: Toxicol Appl Pharmacol
  doi: 10.1016/j.taap.2010.10.025
– volume: 14
  start-page: 281
  year: 2005
  ident: 319_CR28
  publication-title: Eurp J Cancer Prev
  doi: 10.1097/00008469-200506000-00014
– volume: 48
  start-page: 1211
  issue: 9
  year: 2010
  ident: 319_CR14
  publication-title: Free Radic Biol Med
  doi: 10.1016/j.freeradbiomed.2010.02.004
– volume: 89
  start-page: 431
  year: 2006
  ident: 319_CR8
  publication-title: Toxicol Sci
  doi: 10.1093/toxsci/kfj030
– volume: 40
  start-page: 352
  issue: 3
  year: 2002
  ident: 319_CR35
  publication-title: Indian J Exp Biol
– volume: 45
  start-page: 490
  year: 2007
  ident: 319_CR7
  publication-title: Clin Toxicol (Phila)
  doi: 10.1080/15563650701354119
– volume: 115
  start-page: 599
  year: 2007
  ident: 319_CR12
  publication-title: Environ Health Perspect
  doi: 10.1289/ehp.9734
– volume: 234–235
  start-page: 301
  issue: 1–2
  year: 2002
  ident: 319_CR20
  publication-title: Mol Cell Biochem
  doi: 10.1023/A:1015927406142
– ident: 319_CR29
  doi: 10.1016/j.plaphy.2009.05.007
– volume: 37
  start-page: 23
  year: 2015
  ident: 319_CR30
  publication-title: Genes Environ
  doi: 10.1186/s41021-051-0023-7
– volume: 69
  start-page: 2966
  issue: 7
  year: 2009
  ident: 319_CR44
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-08-3418
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Snippet Oxidative stress is significantly associated with chronic arsenic exposure in persons exposed to moderate-to-high level of environmental arsenic. However, the...
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SubjectTerms 8-Hydroxydeoxyguanosine
Aquatic Pollution
Arsenic
Carbonyls
Creatinine
DNA damage
DNA methylation
Drinking water
Earth and Environmental Science
Environment
Environmental Health
Enzymes
Exposure
Gene polymorphism
Glutathione
Glutathione transferase
GSTM1 protein
GSTT1 protein
Laboratory animals
Metabolism
Nonparametric statistics
Original Paper
Oxidation
Oxidative stress
Pollution
Polymorphism
Proteins
Urine
Waste Water Technology
Water and Health
Water Management
Water Pollution Control
Water Quality/Water Pollution
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Title Role of Glutathione-S-Transferase Polymorphism on Arsenic-Induced Protein Carbonylation and Urinary Deoxy Guanosine Status
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