Rapid detection of Escherichia coli and Salmonella typhimurium by surface-enhanced Raman scattering

In this paper, the surface-enhanced Raman scattering （SERS） is used as an analytical tool for the detection and identi- fication of pathogenic bacteria of Escherichia coli （E. coli） and Salmonella typhimurium （S. typhimurium）. Compared with normal Raman signal, the intensity of SERS signal is greatl...

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Bibliographic Details
Published inOptoelectronics letters Vol. 11; no. 2; pp. 157 - 160
Main Author 苏蓝 张萍 郑大威 汪杨俊琦） 钟儒刚
Format Journal Article
LanguageEnglish
Published Heidelberg Tianjin University of Technology 01.03.2015
Subjects
Lasers
Optical Devices
Optics
Photonics
Physics
Physics and Astronomy
SERS光谱
分析工具
化学计量学
大肠杆菌
快速检测
表面增强拉曼光谱
表面增强拉曼散射
鼠伤寒沙门氏菌
Hierarchical Cluster Analysis
Chloroauric Acid
SERS
SERS Detection
SERS Spectrum
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ISSN1673-1905
1993-5013
DOI10.1007/s11801-015-4216-x

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Summary:In this paper, the surface-enhanced Raman scattering （SERS） is used as an analytical tool for the detection and identi- fication of pathogenic bacteria of Escherichia coli （E. coli） and Salmonella typhimurium （S. typhimurium）. Compared with normal Raman signal, the intensity of SERS signal is greatly enhanced. After processing all SERS data, the ob- vious differences between the SERS spectra of two species are determined. And applying the chemometric tools of principal component analysis and hierarchical cluster analysis （PCA-HCA）, the SERS spectra of two species are dis- tinguished more accurately. The results indicate that SERS analysis can provide a rapid and sensitive method for the detection of pathogenic bacteria.
Bibliography:12-1370/TN
SU Lan , ZHANG Ping, ZHENG Da-wei , WANG Yang-jun-qi , ZHONG Ru-gang （College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China）
In this paper, the surface-enhanced Raman scattering （SERS） is used as an analytical tool for the detection and identi- fication of pathogenic bacteria of Escherichia coli （E. coli） and Salmonella typhimurium （S. typhimurium）. Compared with normal Raman signal, the intensity of SERS signal is greatly enhanced. After processing all SERS data, the ob- vious differences between the SERS spectra of two species are determined. And applying the chemometric tools of principal component analysis and hierarchical cluster analysis （PCA-HCA）, the SERS spectra of two species are dis- tinguished more accurately. The results indicate that SERS analysis can provide a rapid and sensitive method for the detection of pathogenic bacteria.
ISSN:1673-1905
1993-5013
DOI:10.1007/s11801-015-4216-x