Chromium Content in the Human Hip Joint Tissues

• Published in: Biomedical and environmental sciences Vol. 28; no. 2; pp. 89 - 96
• Main Author: Barbara Brodziak-Dopierala Jerzy Kwapulifiski Krzysztof Sobczyk Danuta Wiechula
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.02.2015; School of Pharmacy with the Division of Laboratory Medicine, Department of Toxicology, Medical University of Silesia, 4 Jagiellonska, Str. 41-200 Sosnowiec, Poland%Institute of 0ccupational Medicine and Environmental Health, 13 Ko?cielna, Str. 41-200 Sosnowiec, Poland%Municipal Hospital, Department of Traumatic Surgery, May-1 Str. 41-100 Siemianowice Slaskie, Poland
• Subjects: Aged; Bone and Bones - chemistry; Cancellous bone; Cartilage, Articular - chemistry; Chromium; Chromium - chemistry; Cortical bone; Environmental Exposure; Environmental Pollutants - chemistry; Environmental Pollutants - metabolism; Female; Femur head; Hip joint; Hip Joint - chemistry; Humans; Male; Middle Aged; Smoking; 原子吸收光谱法; 松质骨; 解剖部位; 铬含量; 非参数检验; 骨性关节炎; 骨组织; 髋关节; Hip joint; Chromium; Cancellous bone; Cortical bone; Femur head
• ISSN: 0895-3988; 2214-0190
• DOI: 10.3967/bes2015.011

Objective Chromium has many important functions in the human body. For the osseous tissue, its role has not been clearly defined. This study was aimed at determining chromium content in hip joint tissues. Methods A total of 91 hip joint samples were taken in this study, including 66 from females and 25 from males. The sample tissues were separated according to their anatomical parts. The chromium content was determined by the AAS method. The statistical analysis was performed with U Mann-Whitney＇s non-parametric test, P〈0.05. Results The overall chromium content in tissues of the hip joint in the study subjects was as follows： 5.73 μg/g in the articular cartilage, 5.33 μ/g in the cortical bone, 27.86 μ/g in the cancellous bone, 5.95 μg/8 in the fragment of the cancellous bone from the intertrochanteric region, and 2.28 μ/g in the joint capsule. The chromium contents were observed in 2 group patients, it was 7.04 μ/g in people with osteoarthritis and 22.59 μ/g in people with fractures. Conclusion The observed chromium content was highest in the cancellous bone and the lowest in the joint capsule. Chromium content was significantly different between the people with hip joint osteoarthritis and the people with femoral neck fractures.