Synthesis and characterization of modified chitosan as a promising material for enterosorption of heavy metal ions

• Published in: Carbohydrate research Vol. 545; p. 109255
• Main Authors: Fatullayeva, S.S., Tagiyev, D.B., Zeynalov, N.A., Raucci, M.G., Amendola, E., d’Ayala, G. Gomez, Guliyev, A.D., Tagiyev, ShD, Marcedula, M.R., Demitri, C., Guliyeva, A.R., Suleymanova, R.H.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.11.2024
• Subjects: Adsorption; Characterization; Chemical modification; Chitosan; Chitosan - chemical synthesis; Chitosan - chemistry; Functional group; Ions - chemistry; Metals, Heavy - chemistry; Quaternization; Structure; Synthesis; Characterization; Chemical modification; Synthesis; Quaternization; Chitosan; Structure; Functional group
• ISSN: 0008-6215; 1873-426X; 1873-426X
• DOI: 10.1016/j.carres.2024.109255

Currently, an important ecological problem is environmental pollution and its negative impact on living organisms, the consequences of which are deterioration in general health and the manifestation of various diseases, poisoning, endo- and exotoxicosis. Enterosorption method was proposed as a promising method for removing toxic substances from the living organisms using enterosorbents which can absorb various toxic substances of endogenous and exogenous nature in the lumen of the gastrointestinal tract. It has been proposed to use polymer-containing enterosorbents for eliminating of heavy metals from the organism. The purpose of this research was to synthesize a quaternized derivative of chitosan, specifically N-(2-hydroxybenzyl)-N-ethyl-N-methyl chitosan chloride (Q-CHS). The synthesis of Q-CHS involved the formation of a Schiff base, followed by the quaternization of the amino group of chitosan (CHS). The structures of both pure CHS and quaternized CHS were studied using various physico-chemical methods, including FTIR, NMR, XRD, SEM, DSC and TGA analyses in order to determine the structure and confirm the formation of the final product. [Display omitted] •Search and development of new effective, easily accessible, harmless and improved compositions of enterosorbents (for removing toxic substances from the living organisms in the lumen of the gastrointestinal tract) is a topical question today.•Chitosan, containing reactive functional (amino and hydroxyl) groups, can be subject to various modifications in order to improve certain properties and, thus, can find wide application.•Quaternized chitosan was successfully synthesized with the purpose to use it in future as an enterosorbent.