Association between hemoglobin level and cognitive profile in old adults: A cross‐sectional survey

An inverted U‐shaped curve association may exist between Hemoglobin (HGB) level and global cognitive profile. High hemoglobin levels within the normal range may improve the cognitive function in the elderly. Both low and high HGB levels were shown to independently increase the risk of dementia in la...

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Published inInternational journal of geriatric psychiatry Vol. 37; no. 9
Main Authors Yang, Yaqi, Liu, Shuai, Gan, Jinghuan, Zhu, Han, Du, Xiaoshan, Chen, Zhichao, Ma, Lingyun, Meng, Qingbo, Yang, Fan, Chen, Hui, Ji, Yong
Format Journal Article
LanguageEnglish
Published England Wiley Subscription Services, Inc 01.09.2022
Subjects
Anemia
Cognitive ability
Cross-sectional studies
Dementia
Dementia disorders
Females
Geriatric psychiatry
Hemoglobin
Males
Regression analysis
Surveys
dementia
hyperhemoglobinemia
cognitive impairment
U-shaped curve
anemia
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ISSN0885-6230
1099-1166
1099-1166
DOI10.1002/gps.5806

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Summary:An inverted U‐shaped curve association may exist between Hemoglobin (HGB) level and global cognitive profile. High hemoglobin levels within the normal range may improve the cognitive function in the elderly. Both low and high HGB levels were shown to independently increase the risk of dementia in later life. An abnormal HGB level had greater effects in females, resulting in higher risk of dementia for females with anemia or hyperhemoglobinemia than males.
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ISSN:0885-6230
1099-1166
1099-1166
DOI:10.1002/gps.5806