Primary Breast Osteosarcoma: A Case Report and Literature Review

Abstract Primary breast osteosarcomas are rare. We report an unusual case of a 58-year-old female presenting with a right breast lump for 1 month. Mammography showed an ill-defined, heterogeneous, and coarse calcification measuring 4 cm over the upper inner quadrant of the right breast. She received...

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Bibliographic Details
Published inJournal of cancer research and practice Vol. 11; no. 4; pp. 144 - 147
Main Authors Tsai, Tsung-Han, Huang, Hsuan-Ying, Su, Yu-Li
Format Journal Article
LanguageEnglish
Published India Wolters Kluwer - Medknow 01.10.2024
Medknow Publications and Media Pvt. Ltd
Wolters Kluwer Medknow Publications
Edition2
Subjects
Case Report
extraosseous osteossarcoma
Lumpectomy
Mammography
Osteosarcoma
primary breast osteosarcoma
Taiwan
Case report
extraosseous osteossarcoma
primary breast osteosarcoma
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ISSN2311-3006
2311-3006
DOI10.4103/ejcrp.eJCRP-D-24-00012

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Summary:Abstract Primary breast osteosarcomas are rare. We report an unusual case of a 58-year-old female presenting with a right breast lump for 1 month. Mammography showed an ill-defined, heterogeneous, and coarse calcification measuring 4 cm over the upper inner quadrant of the right breast. She received an upfront partial mastectomy after core needle biopsy showed osteoid-like tissue with the presence of atypical cells and some multinucleated giant cells. The final pathology revealed Grade 3 extraosseous osteosarcoma, osteoblastic type. Four cycles of adjuvant doxorubicin and cisplatin followed by radiotherapy were given due to the close surgical margin. She has since been free of recurrence for 3 years.
ISSN:2311-3006
2311-3006
DOI:10.4103/ejcrp.eJCRP-D-24-00012