Noninvasive measurement of body temperature distribution during radiofrequency hyperthermia for cancer treatment

• Published in: Journal of mechanical science and technology Vol. 37; no. 11; pp. 6065 - 6075
• Main Authors: Park, Ki Sun, Hossain, M. Tamim, Kim, Jung Kyung, Lee, Hee Joon
• Format: Journal Article
• Language: English
• Published: Seoul Korean Society of Mechanical Engineers 01.11.2023; Springer Nature B.V; 대한기계학회
• Subjects: Body temperature; Cancer; Control; Dynamical Systems; Electrodes; Engineering; Hyperthermia; Industrial and Production Engineering; Mechanical Engineering; Necrosis; Original Article; Radio frequency; Temperature distribution; Vibration; 기계공학; Radiofrequency hyperthermia; Temperature; Specific absorption rate; Noninvasive measurement; Cancer treatment
• ISSN: 1738-494X; 1976-3824
• DOI: 10.1007/s12206-023-1045-x

Radiofrequency hyperthermia is a treatment that involves heating cancer tissue by supplying a 10 to 100 MHz radiofrequency current through an electrode, aiming to induce thermal necrosis of cancer cells. However, this process also heats normal cells, making it crucial to monitor the temperature inside the patient’s body to prevent thermal necrosis of healthy tissues. Accurate noninvasive measurement of the internal body temperature is of utmost importance in radiofrequency hyperthermia. To achieve this, a numerical study was conducted to predict a patient’s body temperature by solving the Laplace and Pennes’ bioheat transfer equations for the specific area where the cancer is located. An in-house numerical program was developed and applied to radiofrequency hyperthermia to find the optimal electrode location, enhancing the necrosis rate of cancer cells while avoiding thermal damage to normal tissues.