Influence of plasma calcium and vitamin D on bone collagen Effects of lysine hydroxylation and crosslink formation

In chick bone collagen the degree of lysine hydroxylation and the magnitude of the crosslink ratio dihydroxylysinonorleucine/hydroxylysinonorluecine were both found to be inversely related to the concentration of plasma calcium. Lysin hydroxylation was also affected by a second factor related to vit...

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Bibliographic Details
Published inBiochimica et biophysica acta Vol. 588; no. 1; pp. 169 - 173
Main Authors Dickson, I.R., Eyre, D.R., Kodicek, E.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 15.11.1979
Subjects
Animals
Bone and Bones - metabolism
Ca 2
Calcium - blood
Chicken bone
Chickens - metabolism
chicks
Cholecalciferol - therapeutic use
Collagen - metabolism
Collagen crosslinks
Hydroxylysine - metabolism
Lysine hydroxylation
Male
Vitamin D
Vitamin D Deficiency - blood
Vitamin D Deficiency - prevention & control
Chicken bone
Lysine hydroxylation
Vitamin D
Collagen crosslinks
Ca 2
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ISSN0304-4165
0006-3002
1872-8006
DOI10.1016/0304-4165(79)90381-7

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Summary:In chick bone collagen the degree of lysine hydroxylation and the magnitude of the crosslink ratio dihydroxylysinonorleucine/hydroxylysinonorluecine were both found to be inversely related to the concentration of plasma calcium. Lysin hydroxylation was also affected by a second factor related to vitamine D status.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0304-4165
0006-3002
1872-8006
DOI:10.1016/0304-4165(79)90381-7