Synthesis, Characterisation and Biological Activity of New Co, Ni, Zn and Cd Polymeric Complexes Derived from Dithiocarbamate Ligand

• Published in: Majallat Baghdād lil-ʻulūm Vol. 21; no. 2
• Main Authors: Ahmed, Riyadh M., Rahman, Sarah S. Abdul, Badri, Dhefaf H., Sultan, Khawla M., Majeed, Ismaeel Y., Kamil, Ghada M.
• Format: Journal Article
• Language: English
• Published: University of Baghdad, College of Science for Women 01.01.2024
• Subjects: Biological, Ligand, Polymeric, Spectroscopy, Tetrazole
• ISSN: 2078-8665; 2411-7986
• DOI: 10.21123/bsj.2023.8038

Synthesis of a new class of Schiff-base ligand with a tetrazole moiety to form polymeric metal complexes with CoII, NiII, ZnII, and CdII ions has been demonstrated. The ligand was synthesised by a multi-steps by treating 5-amino-2-chlorobenzonitrile and cyclohexane -1,3-dione, the 5,5'-(((1E,3E)-cyclohexane-1,3-diylidene)bis(azanylylidene))bis(2-chlorobenzonitrile) was obtained. The precursor (M) was prepared  from the reaction 5,5'-(((1E,3E)-cyclohexane-1,3-diylidene)bis(azanylylidene))bis(2-chlorobenzonitrile) with NaN3 to obtained (1E,3E)-N1,N3-bis(4-chloro-3-(1H-tetrazol-5-yl)phenyl)cyclohexane-1,3-diimine (N). By reacting the precursor (M) with CS2/KOH, the required ligand was synthesised. Co (II), Ni (II), Zn (II), Cd (II) ions produce polymeric metal complexes with the formula [M(L)]n when they react with the ligand (L). These complexes were synthesised using the same methods. The geometrical structure of ligand and their polymeric complexes were determined using FTIR, 1H, 13C-NMR, electronic spectroscopy, ESMS, magnetic susceptibility, metal and chloride contents, micro elemental analysis and conductance. From the results ,we conclude that the L-complexes demonstrate the production of four-coordinate complexes with tetrahedral geometry for Co(II), Zn(II), and Cd(II), and square planer geometry for Ni (II). We examined the antibacterial activity of both ligand and complexes with two types of bacteria positive (Bacillus stubtili and Staphylococcus aureus ) and negative (Escherichia coli and Pseudomonas aeruginosa ) with concentration 10-2.