Extended time of cold ischemia and its influence on the physiological function of human adult pancreatic islets

In this study we compared the effects of duration of cold ischemia (longer and shorter ischemia) on the yield, viability and preservation of the physiological function and insulin secretion of adult human pancreatic islets in short-term (seven days) culture. Based on the tested parameters, we establ...

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Published inArchives of biological sciences Vol. 63; no. 4; pp. 1007 - 1013
Main Authors Nikolic, D.M., Djordjevic, P.B., Radak, Dj, Lackovic, Vesna, Bajcetic, Milos, Milic, Gordana, Gostiljac, D., Ilic, M., Raketic, Nevenka, Stojiljkovic, Vesna, Grubor, Nikica, Jovanovic, M.D., Latincic, S.M.
Format Journal Article
LanguageEnglish
Published University of Belgrade, University of Novi Sad 2011
Subjects
Extended cold ischemia time
human adult pancreatic islets
islet preservation
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ISSN0354-4664
1821-4339
DOI10.2298/ABS1104007N

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Summary:In this study we compared the effects of duration of cold ischemia (longer and shorter ischemia) on the yield, viability and preservation of the physiological function and insulin secretion of adult human pancreatic islets in short-term (seven days) culture. Based on the tested parameters, we established that there are no major differences between these two test groups and that the storage and transport of pancreatic tissue in physiological solution at 4oC gives quite satisfactory results. nema PR Projekat Ministarstva nauke Republike Srbije, br. 145088 i 41002
ISSN:0354-4664
1821-4339
DOI:10.2298/ABS1104007N