The Clinicopathological Features of Hepatic Metastasis of Colorectal Cancer

• Published in: Nippon Daicho Komonbyo Gakkai Zasshi Vol. 41; no. 7; pp. 982 - 986
• Main Authors: Mori, M., Kikuchi, T., Kajiwara, T., Kumazawa, K., Matsumoto, N., Umeda, H., Makita, M., Azuhata, H., Haga, S., Kato, H.
• Format: Journal Article
• Language: English; Japanese
• Published: The Japan Society of Coloproctology 1988
• ISSN: 0047-1801; 1882-9619; 1882-9619
• DOI: 10.3862/jcoloproctology.41.982

The clinicopathological features of hepatic metastasis of colorectal cancer were investi-gated. The subjects were 267 patients with colorectal cancer who underwent surgery between 1975 and 1985. Among these patients, hepatic metastasis was found during surgery in 29 and after surgery in 13, totaling 42 (15.8%). In relation to sex, the percentage of hepatic metastasis was 19.2% among males and 12.4% among femals, showing a predominance in male patients. With regard to age, such metastasis was most freruent among male patients in their 60s and among female patients in their 50s. The tumor was located in the colon in 16.2 % of patients and in the rectum in 14.8 %, showing no particular difference between the two sites. There were no biased patterns in relation to the histologic type or the maximum diameter of the tumor. The depth of wall invasion was judged to be ss(a1), or severer in all hepatic metastasis cases. Lymphatic invasion was positive in 18.7% of patients and negativg in 8.9%, while venous invasion was positive in 21.4 % and negative in 10.1 %. Lymph node'metastasis was positive in 21.2% and negative in 8.3%. The percentave of hepatic metastasis was significantly higher in positive cases than in negative cases with regard to all the above parameters. Thus, hepatic metaseasis was found to be closely related to the depth of wall invasion and vascular invasion.