Effect of loop on the stability of intramolecular triplex DNA
Conformation stabilities of intramolecular triple-helical DNAs (intra-tnplex DNAs: 5-d(TC)6-d(T)m-d(CT)6-d(C)n-d(AG)6-3’,where m and n are chosen to be 4 and 3) have been examined by molecular mechanics.The four intra-triplexes (H-DNAs) are compared with the mtermolecular triplexes d(TC)6 * d ( AG)6...
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| Published in | Science China. Chemistry Vol. 40; no. 6; pp. 650 - 656 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
Heidelberg
Springer Nature B.V
01.12.1997
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1674-7291 1006-9291 1869-1870 1862-2771 |
| DOI | 10.1007/BF02875484 |
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| Abstract | Conformation stabilities of intramolecular triple-helical DNAs (intra-tnplex DNAs: 5-d(TC)6-d(T)m-d(CT)6-d(C)n-d(AG)6-3’,where m and n are chosen to be 4 and 3) have been examined by molecular mechanics.The four intra-triplexes (H-DNAs) are compared with the mtermolecular triplexes d(TC)6 * d ( AG)6 d(CT)6.The results revealed that loops do not significantly influence the mtratriplex conformations,loop conformations,however,depend partly on its length.Loop also makes strand Ⅱ of every intra-triplex DNA longer than that of the inter-triplex DNA.Most of residue sugar conformations of triple-helical DNAs are S-type,there aiso exist,however,N-type conformation and the conformations between S-type and N-type Possible models of the five triplex DNAs are presented. |
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| AbstractList | Conformation stabilities of intramolecular triple-helical DNAs (intra-triplex DNAs: 5′-d(TC)6- d(T)m-d(CT)6-d(C)n-d(AG)6-3′, wherem andn are chosen to be 4 and 3) have been examined by molecular mechanics. The four intra-triplexes (H-DNAs) are compared with the intermolecular triplexes d(TC)6 * d(AG)6 · d(CT)6. The results revealed that loops do not significantly influence the intratriplex conformations, loop conformations, however, depend partly on its length. Loop also makes strand II of every intra-triplex DNA longer than that of the inter-triplex DNA. Most of residue sugar conformations of triple-helical DNAs are S-type, there also exist, however, N-type conformation and the conformations between S-type and N-type. Possible models of the five triplex DNAs are presented. Conformation stabilities of intramolecular triple-helical DNAs (intra-tnplex DNAs: 5-d(TC)6-d(T)m-d(CT)6-d(C)n-d(AG)6-3’,where m and n are chosen to be 4 and 3) have been examined by molecular mechanics.The four intra-triplexes (H-DNAs) are compared with the mtermolecular triplexes d(TC)6 * d ( AG)6 d(CT)6.The results revealed that loops do not significantly influence the mtratriplex conformations,loop conformations,however,depend partly on its length.Loop also makes strand Ⅱ of every intra-triplex DNA longer than that of the inter-triplex DNA.Most of residue sugar conformations of triple-helical DNAs are S-type,there aiso exist,however,N-type conformation and the conformations between S-type and N-type Possible models of the five triplex DNAs are presented. |
| Author | 杨林静 白春礼 李任植 汪新文 王琛 |
| AuthorAffiliation | Institute of Chemistry Chinese Academy of Sciences Beijing 100080 China China |
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| Cites_doi | 10.1002/jcc.540070216 10.1006/jmbi.1993.1241 10.1021/bi00396a042 10.1016/0079-6107(92)90007-S 10.1021/ar50044a001 10.1073/pnas.85.17.6242 10.1021/bi00053a008 10.1107/S0365110X59002389 10.1016/0022-2836(68)90073-9 10.1093/nar/16.24.11795 10.1021/bi00444a049 10.1093/nar/23.7.1260 10.1016/0022-2836(74)90498-7 10.1016/0022-2860(95)09024-X 10.1021/ja01565a074 |
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| References | Z. A. Daina (BF02875484_CR11) 1995; 23 E. Dorothy (BF02875484_CR8) 1987; 26 S. Arott (BF02875484_CR3) 1974; 88 A. R. Morgan (BF02875484_CR2) 1968; 37 D. Michel (BF02875484_CR15) 1992; 20 A. Dorothy (BF02875484_CR7) 1993; 32 L. B. Robert (BF02875484_CR6) 1971; 4 M. J. J. Blomers (BF02875484_CR9) 1989; 28 G. Felsenfeld (BF02875484_CR1) 1957; 79 S. J. Weiner (BF02875484_CR16) 1986; 7 M. Mary (BF02875484_CR10) 1988; 85 C. H. Stephen (BF02875484_CR13) 1988; 16 Lee Imshik (BF02875484_CR17) 1997; 40 J. Volker (BF02875484_CR5) 1993; 230 Cheng Yuen-Ktt (BF02875484_CR12) 1992; 58 K. Hoogsteen (BF02875484_CR4) 1959; 12 Y. Fang (BF02875484_CR14) 1995; 372 |
| References_xml | – volume: 40 start-page: 113 year: 1997 ident: BF02875484_CR17 publication-title: Science in China – volume: 7 start-page: 765 year: 1986 ident: BF02875484_CR16 publication-title: J. Comp. Chem. doi: 10.1002/jcc.540070216 – volume: 230 start-page: 1278 year: 1993 ident: BF02875484_CR5 publication-title: J. Mol. Biol. doi: 10.1006/jmbi.1993.1241 – volume: 26 start-page: 7150 year: 1987 ident: BF02875484_CR8 publication-title: Biochemistry doi: 10.1021/bi00396a042 – volume: 58 start-page: 225 year: 1992 ident: BF02875484_CR12 publication-title: Prog. Biophys. Molec. Biol. doi: 10.1016/0079-6107(92)90007-S – volume: 4 start-page: 265 year: 1971 ident: BF02875484_CR6 publication-title: Accounts of Chemical Research doi: 10.1021/ar50044a001 – volume: 85 start-page: 6242 year: 1988 ident: BF02875484_CR10 publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.85.17.6242 – volume: 32 start-page: 436 year: 1993 ident: BF02875484_CR7 publication-title: Biochemistry doi: 10.1021/bi00053a008 – volume: 12 start-page: 822 year: 1959 ident: BF02875484_CR4 publication-title: Acta Crystallogr. doi: 10.1107/S0365110X59002389 – volume: 37 start-page: 63 year: 1968 ident: BF02875484_CR2 publication-title: J. Mol. Biol. doi: 10.1016/0022-2836(68)90073-9 – volume: 16 start-page: 11795 year: 1988 ident: BF02875484_CR13 publication-title: Nucleic Acids Research doi: 10.1093/nar/16.24.11795 – volume: 28 start-page: 7491 year: 1989 ident: BF02875484_CR9 publication-title: Biochemistry doi: 10.1021/bi00444a049 – volume: 23 start-page: 1260 year: 1995 ident: BF02875484_CR11 publication-title: Nucleic Acids Research doi: 10.1093/nar/23.7.1260 – volume: 88 start-page: 509 year: 1974 ident: BF02875484_CR3 publication-title: J. Mol. Biol. doi: 10.1016/0022-2836(74)90498-7 – volume: 372 start-page: 241 year: 1995 ident: BF02875484_CR14 publication-title: J. Mol. Str. doi: 10.1016/0022-2860(95)09024-X – volume: 20 start-page: 439 year: 1992 ident: BF02875484_CR15 publication-title: The long repetitive polypurinelpolyprimidine sequence (TTCCC)48 forms DNA triplex with Pu-Pu-Py base triplets in vivo, Nucleic Acids Research – volume: 79 start-page: 2023 year: 1957 ident: BF02875484_CR1 publication-title: J. Amer. Chem. Soc. doi: 10.1021/ja01565a074 |
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| Snippet | Conformation stabilities of intramolecular triple-helical DNAs (intra-tnplex DNAs: 5-d(TC)6-d(T)m-d(CT)6-d(C)n-d(AG)6-3’,where m and n are chosen to be 4 and... Conformation stabilities of intramolecular triple-helical DNAs (intra-triplex DNAs: 5′-d(TC)6- d(T)m-d(CT)6-d(C)n-d(AG)6-3′, wherem andn are chosen to be 4 and... |
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| SubjectTerms | DNA intra-triplex loop mechanics molecular stability |
| Title | Effect of loop on the stability of intramolecular triplex DNA |
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