Circulating MicroRNA-21 is Downregulated in Patients with Metabolic Syndrome

The microRNA-21 （miR-21） is known to play a major role in cancer progression; however, its function in the cardiovascular system appears to be even more complex and conflicting. To characterize miR-21 expression in the plasma of individuals with or without metabolic syndrome （MetS）, 58 MetS cases an...

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Published inBiomedical and environmental sciences Vol. 29; no. 5; pp. 385 - 389
Main Authors HE, Qing Fang, WANG, Li Xin, ZHONG, Jie Ming, HU, Ru Ying, FANG, Le, WANG, Hao, GONG, Wei Wei, ZHANG, Jie, PAN, Jing, YU, Min
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.05.2016
Subjects
Adult
Aged
Down-Regulation
Female
Humans
Male
Metabolic Syndrome - blood
Metabolic Syndrome - etiology
Metabolic Syndrome - genetics
MicroRNAs - blood
MicroRNAs - genetics
MicroRNAs - metabolism
Middle Aged
Real-Time Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
Risk Factors
代谢综合征
大都会
循环
心血管系统
患者
等离子体
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ISSN0895-3988
2214-0190
DOI10.3967/bes2016.050

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Summary:The microRNA-21 （miR-21） is known to play a major role in cancer progression; however, its function in the cardiovascular system appears to be even more complex and conflicting. To characterize miR-21 expression in the plasma of individuals with or without metabolic syndrome （MetS）, 58 MetS cases and 96 non-MetS controls were investigated.
Bibliography:The microRNA-21 （miR-21） is known to play a major role in cancer progression; however, its function in the cardiovascular system appears to be even more complex and conflicting. To characterize miR-21 expression in the plasma of individuals with or without metabolic syndrome （MetS）, 58 MetS cases and 96 non-MetS controls were investigated.
11-2816/Q
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ISSN:0895-3988
2214-0190
DOI:10.3967/bes2016.050