V. Study of the Experimental Oligoganglionosis of the Colon

For the investigation of pathophysiology in the oligoganglionosis of colon, the experimental destruction of Auerbach's plexus by temporary hypoxia was induced in dogs. Compared the EMG of the oligoganglionic segments with normal EMG which was classified into five basic patterns by ourselves, th...

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Published inNippon Daicho Komonbyo Gakkai Zasshi Vol. 31; no. 3; pp. 230 - 242,302
Main Author Ando, H.
Format Journal Article
LanguageEnglish
Published The Japan Society of Coloproctology 1978
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ISSN0047-1801
1882-9619
1882-9619
DOI10.3862/jcoloproctology.31.230

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Summary:For the investigation of pathophysiology in the oligoganglionosis of colon, the experimental destruction of Auerbach's plexus by temporary hypoxia was induced in dogs. Compared the EMG of the oligoganglionic segments with normal EMG which was classified into five basic patterns by ourselves, the frequent appearance of spike bursts was characteristic, suggesting the role of Auerbach's plexus as inhibitor against the electric activity of the colon. This spike burst was inhibited by β stimulator and accelerated by β blocking agent. By X-Ray examination, this oligoganglionic segment has shown no narrowing as like as Hirschsprung's disease but some degree of disturbed bowel movement.
ISSN:0047-1801
1882-9619
1882-9619
DOI:10.3862/jcoloproctology.31.230