A Resected Case of Splenic T-cell Malignant Lymphoma

Methotrexate-lymphoproliferative disorder in rheumatoid arthritis patients treated with Methotrexate. We reported a case of splenic T-cell malignant lymphoma in a patient with rheumatoid arthritis treated with Methotrexate. A 73-year-old woman treated with Methotrexate for 10 years showed high level...

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Bibliographic Details
Published inNippon Shokaki Geka Gakkai zasshi Vol. 40; no. 11; pp. 1834 - 1838
Main Authors Yoshioka, Ryuji, Dabanaka, Ken, Akimori, Toyoichi, Maeda, Hiromichi, Hanazaki, Kazuhiro, Namikawa, Tsutomu, Kobayashi, Michiya, Okabayashi, Takehiro, Okamoto, Ken, Sugimoto, Tateki
Format Journal Article
LanguageJapanese
Published The Japanese Society of Gastroenterological Surgery 2007
Subjects
hand-assited laparoscopic splenectomy
methotrexate-associated lymphoproliferative disorder
T-cell malignant lymphoma
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ISSN0386-9768
1348-9372
DOI10.5833/jjgs.40.1834

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Summary:Methotrexate-lymphoproliferative disorder in rheumatoid arthritis patients treated with Methotrexate. We reported a case of splenic T-cell malignant lymphoma in a patient with rheumatoid arthritis treated with Methotrexate. A 73-year-old woman treated with Methotrexate for 10 years showed high levels of CA125 334.8U/ml and IL-2 receptor antibody of 4, 390U/ml. Abdominal contrast-enhanced computed tomography and magnetic resonance imaging showed mass lesions in the spleen. FDG-PET showed splenic FDG accumulation. Based on a diagnosis of malignant splenic lymphoma, we conducted manually assisted laparoscopic splenectomy.
ISSN:0386-9768
1348-9372
DOI:10.5833/jjgs.40.1834